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Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention

Recent translational studies highlighted the inhibition of transforming growth factor (TGF)-β signaling as a promising target to treat pulmonary arterial hypertension (PAH). However, it remains unclear whether alterations in TGF-β signaling are consistent between PAH patients and animal models. Ther...

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Detalles Bibliográficos
Autores principales:	Sanada, Takayuki Jujo, Sun, Xiao-Qing, Happé, Chris, Guignabert, Christophe, Tu, Ly, Schalij, Ingrid, Bogaard, Harm-Jan, Goumans, Marie-José, Kurakula, Kondababu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825543/ https://www.ncbi.nlm.nih.gov/pubmed/33419137 http://dx.doi.org/10.3390/cells10010084

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