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Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other sp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825634/ https://www.ncbi.nlm.nih.gov/pubmed/33419224 http://dx.doi.org/10.3390/jof7010030 |
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author | Danion, François van Rhijn, Norman Dufour, Alexandre C. Legendre, Rachel Sismeiro, Odile Varet, Hugo Olivo-Marin, Jean-Christophe Mouyna, Isabelle Chamilos, Georgios Bromley, Michael Beauvais, Anne Latgé, Jean-Paul |
author_facet | Danion, François van Rhijn, Norman Dufour, Alexandre C. Legendre, Rachel Sismeiro, Odile Varet, Hugo Olivo-Marin, Jean-Christophe Mouyna, Isabelle Chamilos, Georgios Bromley, Michael Beauvais, Anne Latgé, Jean-Paul |
author_sort | Danion, François |
collection | PubMed |
description | Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other species of filamentous fungi. We show here that the germination of A. fumigatus is asynchronous. If the nutritional environment and extensive gene deletions can modify the germination parameters for A. fumigatus, the asynchrony is maintained in all germinative conditions tested. Even though the causes for this asynchrony of conidial germination remain unknown, asynchrony is essential for the completion of the biological cycle of this filamentous fungus. |
format | Online Article Text |
id | pubmed-7825634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78256342021-01-24 Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring Danion, François van Rhijn, Norman Dufour, Alexandre C. Legendre, Rachel Sismeiro, Odile Varet, Hugo Olivo-Marin, Jean-Christophe Mouyna, Isabelle Chamilos, Georgios Bromley, Michael Beauvais, Anne Latgé, Jean-Paul J Fungi (Basel) Article Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other species of filamentous fungi. We show here that the germination of A. fumigatus is asynchronous. If the nutritional environment and extensive gene deletions can modify the germination parameters for A. fumigatus, the asynchrony is maintained in all germinative conditions tested. Even though the causes for this asynchrony of conidial germination remain unknown, asynchrony is essential for the completion of the biological cycle of this filamentous fungus. MDPI 2021-01-06 /pmc/articles/PMC7825634/ /pubmed/33419224 http://dx.doi.org/10.3390/jof7010030 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Danion, François van Rhijn, Norman Dufour, Alexandre C. Legendre, Rachel Sismeiro, Odile Varet, Hugo Olivo-Marin, Jean-Christophe Mouyna, Isabelle Chamilos, Georgios Bromley, Michael Beauvais, Anne Latgé, Jean-Paul Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title | Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title_full | Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title_fullStr | Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title_full_unstemmed | Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title_short | Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring |
title_sort | aspergillus fumigatus, one uninucleate species with disparate offspring |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825634/ https://www.ncbi.nlm.nih.gov/pubmed/33419224 http://dx.doi.org/10.3390/jof7010030 |
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