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Reversing oncogenic transformation with iron chelation

Cancer cells accumulate iron to supplement their aberrant growth and metabolism. Depleting cells of iron by iron chelators has been shown to be selectively cytotoxic to cancer cells in vitro and in vivo. Iron chelators are effective at combating a range of cancers including those which are difficult...

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Detalles Bibliográficos
Autores principales: Abdelaal, Gina, Veuger, Stephany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825639/
https://www.ncbi.nlm.nih.gov/pubmed/33520115
http://dx.doi.org/10.18632/oncotarget.27866