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Indoxyl Sulfate Mediates the Low Inducibility of the NLRP3 Inflammasome in Hemodialysis Patients

The NLRP3 inflammasome is responsible for the maturation of caspase-1 and interleukin-1β (IL-1β). Despite the study about basal activity of the NLRP3 inflammasome in hemodialysis (HD) patients, little is known about its inducibility in the milieu of uremia. Peripheral blood mononuclear cells (PBMCs)...

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Detalles Bibliográficos
Autores principales:	Ho, Li-Chun, Wu, Ting-Yun, Lin, Tsun-Mei, Liou, Hung-Hsiang, Hung, Shih-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825677/ https://www.ncbi.nlm.nih.gov/pubmed/33430226 http://dx.doi.org/10.3390/toxins13010038

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