Cargando…

Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer

SIMPLE SUMMARY: This study was conducted to investigate the clinical significance and prognostic value of KLF5 in a large cohort of Middle Eastern PTC patients and explore its functional role and mechanism in PTC cell lines in vitro and in vivo. We found KLF5 over-expression in PTC patient cases and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pratheeshkumar, Poyil, Siraj, Abdul K., Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Siraj, Sarah, Diaz, Roxanne, Begum, Rafia, Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825749/ https://www.ncbi.nlm.nih.gov/pubmed/33430300 http://dx.doi.org/10.3390/cancers13020185

Ejemplares similares

SUN-132 KLF5 Is a Poor Prognostic Marker and Therapeutic Target for Middle Eastern Papillary Thyroid Carcinoma
por: Al-Kuraya, Khawla S, et al.
Publicado: (2020)

PD-L1 Is an Independent Prognostic Marker in Middle Eastern PTC and Its Expression Is Upregulated by BRAFV600E Mutation
por: Siraj, Abdul K., et al.
Publicado: (2021)

CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells
por: Pratheeshkumar, Poyil, et al.
Publicado: (2021)

Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF/MEK signaling
por: Poyil, Pratheesh Kumar, et al.
Publicado: (2023)

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment
por: Siraj, Abdul Khalid, et al.
Publicado: (2018)

Risk Factors for Cervical Lymph Node Metastasis in Middle Eastern Papillary Thyroid Microcarcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

Bilateral multifocality is an independent predictor of patients’ outcome in Middle Eastern papillary thyroid carcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2023)

Male Sex Is an Independent Predictor of Recurrence-Free Survival in Middle Eastern Papillary Thyroid Carcinoma
por: Siraj, Abdul K., et al.
Publicado: (2022)

Prognostic Significance of COX-2 Overexpression in BRAF-Mutated Middle Eastern Papillary Thyroid Carcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2020)

Loss of ZNF677 Expression Is an Independent Predictor for Distant Metastasis in Middle Eastern Papillary Thyroid Carcinoma Patients
por: Siraj, Abdul K., et al.
Publicado: (2021)

Krupple-Like Factor 5 is a Potential Therapeutic Target and Prognostic Marker in Epithelial Ovarian Cancer
por: Siraj, Abdul K., et al.
Publicado: (2020)

Annual Hazard Rate of Recurrence in Middle Eastern Papillary Thyroid Cancer over a Long-Term Follow-Up
por: Siraj, Abdul K., et al.
Publicado: (2020)

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells
por: Pratheeshkumar, Poyil, et al.
Publicado: (2017)

Whole-Exome Sequencing of Matched Primary and Metastatic Papillary Thyroid Cancer
por: Masoodi, Tariq, et al.
Publicado: (2020)

Lymph node ratio is superior to AJCC N stage for predicting recurrence in papillary thyroid carcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer
por: Siraj, Abdul K., et al.
Publicado: (2023)

Risk Factors for Central Lymph Node Metastases and Benefit of Prophylactic Central Lymph Node Dissection in Middle Eastern Patients With cN0 Papillary Thyroid Carcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

Microscopic Extrathyroidal Extension Results in Increased Rate of Tumor Recurrence and Is an Independent Predictor of Patient’s Outcome in Middle Eastern Papillary Thyroid Carcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2021)

Tumor size is an independent negative prognostic factor for event free survival in children with differentiated thyroid cancer
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

POLE and POLD1 pathogenic variants in the proofreading domain in papillary thyroid cancer
por: Siraj, Abdul K, et al.
Publicado: (2020)

TERT Promoter Mutations Are an Independent Predictor of Distant Metastasis in Middle Eastern Papillary Thyroid Microcarcinoma
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2022)

FoxM1 is an independent poor prognostic marker and therapeutic target for advanced Middle Eastern breast cancer
por: Siraj, Abdul Khalid, et al.
Publicado: (2018)

Predictive risk factors for distant metastasis in pediatric differentiated thyroid cancer from Saudi Arabia
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2023)

Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer
por: Bu, Rong, et al.
Publicado: (2021)

APOBEC SBS13 Mutational Signature—A Novel Predictor of Radioactive Iodine Refractory Papillary Thyroid Carcinoma
por: Siraj, Sarah, et al.
Publicado: (2022)

The Genomic Landscape of Radioactive Iodine Refractory and Avid Papillary Thyroid Carcinomas
por: Al-Kuraya, Khawla Sami, et al.
Publicado: (2021)

Whole Exome-Wide Association Identifies Rare Variants in GALNT9 Associated with Middle Eastern Papillary Thyroid Carcinoma Risk
por: Bu, Rong, et al.
Publicado: (2023)

Differential expression of PD-L1 between primary and metastatic epithelial ovarian cancer and its clinico-pathological correlation
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2021)

PD-L1 Expression Is an Independent Marker for Lymph Node Metastasis in Middle Eastern Endometrial Cancer
por: Siraj, Abdul K., et al.
Publicado: (2021)

The study of Lynch syndrome in a special population reveals a strong founder effect and an unusual mutational mechanism in familial adenomatous polyposis
por: Siraj, Abdul K, et al.
Publicado: (2020)

PTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma
por: Beg, S, et al.
Publicado: (2015)

MED12 is recurrently mutated in Middle Eastern colorectal cancer
por: Siraj, Abdul K, et al.
Publicado: (2018)

Cyclin-dependent kinase 9 (CDK9) predicts recurrence in Middle Eastern epithelial ovarian cancer
por: Parvathareddy, Sandeep Kumar, et al.
Publicado: (2021)

High Expression of Cyclin D1 is an Independent Marker for Favorable Prognosis in Middle Eastern Breast Cancer
por: Siraj, Abdul K, et al.
Publicado: (2021)

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis
por: Hussain, Azhar R., et al.
Publicado: (2017)

Loss of ZNF677 expression is a predictive biomarker for lymph node metastasis in Middle Eastern Colorectal Cancer
por: Siraj, Abdul K., et al.
Publicado: (2021)

Polymorphisms of selected Xenobiotic Genes contribute to the development of Papillary Thyroid Cancer susceptibility in Middle Eastern population
por: Siraj, Abdul K, et al.
Publicado: (2008)

Germline POLE and POLD1 proofreading domain mutations in endometrial carcinoma from Middle Eastern region
por: Siraj, Abdul K., et al.
Publicado: (2019)

PD-L1 Expression Is Associated with Deficient Mismatch Repair and Poor Prognosis in Middle Eastern Colorectal Cancers
por: Siraj, Abdul K., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f3lk9pd4u40h4tserd546lbfar