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Crizotinib Resistance Mediated by Autophagy Is Higher in the Stem-Like Cell Subset in ALK-Positive Anaplastic Large Cell Lymphoma, and This Effect Is MYC-Dependent

SIMPLE SUMMARY: Autophagy is a cell survival and recycling mechanism which protects cancer cells upon therapeutic drug treatment. Here we investigated the impact of autophagy inhibition in a cancer of lymphoid origin, namely ALK-positive anaplastic large cell lymphoma (ALK + ALCL). We inhibited auto...

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Detalles Bibliográficos
Autores principales:	Shang, Chuquan, Hassan, Bardes, Haque, Moinul, Song, Yuqi, Li, Jing, Liu, Dongzhe, Lipke, Eva, Chen, Will, Giuriato, Sylvie, Lai, Raymond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825760/ https://www.ncbi.nlm.nih.gov/pubmed/33430343 http://dx.doi.org/10.3390/cancers13020181

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