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Namodenoson in Advanced Hepatocellular Carcinoma and Child–Pugh B Cirrhosis: Randomized Placebo-Controlled Clinical Trial
SIMPLE SUMMARY: We conducted a phase II randomized placebo-controlled trial to investigate namodenoson, an A3 adenosine-receptor agonist, as 2nd-line treatment for advanced hepatocellular carcinoma and moderate hepatic dysfunction (Child–Pugh [CP] scores of 7–9). The study included 50 patients in th...
Autores principales: | Stemmer, Salomon M., Manojlovic, Nebojsa S., Marinca, Mihai Vasile, Petrov, Petar, Cherciu, Nelly, Ganea, Doina, Ciuleanu, Tudor Eliade, Pusca, Ioana Adriana, Beg, Muhammad Shaalan, Purcell, William T., Croitoru, Adina-Emilia, Ilieva, Rumyana Nedyalkova, Natošević, Sladjana, Nita, Amedeia Lavinir, Kalev, Dimitar Nikolaev, Harpaz, Zivit, Farbstein, Motti, Silverman, Michael H., Bristol, David, Itzhak, Inbal, Fishman, Pnina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825785/ https://www.ncbi.nlm.nih.gov/pubmed/33430312 http://dx.doi.org/10.3390/cancers13020187 |
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