Cargando…

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

BACKGROUND: Patients with COVID-19 pneumonia have an excess of inflammation and increased concentrations of cytokines including interleukin-1 (IL-1). We aimed to determine whether anakinra, a recombinant human IL-1 receptor antagonist, could improve outcomes in patients in hospital with mild-to-mode...

Descripción completa

Detalles Bibliográficos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825875/ https://www.ncbi.nlm.nih.gov/pubmed/33493450 http://dx.doi.org/10.1016/S2213-2600(20)30556-7

Ejemplares similares

Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial
Publicado: (2022)

Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group
por: Hermine, Olivier, et al.
Publicado: (2022)

Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative Group
por: Hermine, Olivier, et al.
Publicado: (2022)

Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial
por: Carlton, Edward Watts, et al.
Publicado: (2020)

Anakinra versus Baricitinib: Different Strategies for Patients Hospitalized with COVID-19 †
por: García-García, José A, et al.
Publicado: (2021)

Anakinra in children and adults with Still’s disease
por: Vastert, Sebastiaan J, et al.
Publicado: (2019)

Azithromycin versus standard care in patients with mild-to-moderate COVID-19 (ATOMIC2): an open-label, randomised trial
por: Hinks, Timothy S C, et al.
Publicado: (2021)

Critical Care Cycling Study (CYCLIST) trial protocol: a randomised controlled trial of usual care plus additional in-bed cycling sessions versus usual care in the critically ill
por: Nickels, Marc R, et al.
Publicado: (2017)

Opportunistic screening versus usual care for detection of atrial fibrillation in primary care: cluster randomised controlled trial
por: Uittenbogaart, Steven B, et al.
Publicado: (2020)

OUTdoor Swimming as a nature-based Intervention for DEpression (OUTSIDE): study protocol for a feasibility randomised control trial comparing an outdoor swimming intervention to usual care for adults experiencing mild to moderate symptoms of depression
por: Massey, Heather, et al.
Publicado: (2023)

Effect of tocilizumab versus standard of care in adults hospitalized with moderate-severe COVID-19 pneumonia
por: Cardona-Pascual, Ignacio, et al.
Publicado: (2022)

Effect of tocilizumab versus standard of care in adults hospitalized with moderate-severe COVID-19 pneumonia
por: Cardona-Pascual, Ignacio, et al.
Publicado: (2022)

Effect of tocilizumab versus standard of care in adults hospitalized with moderate-severe COVID-19 pneumonia
por: Aomar-Millán, Ismael F., et al.
Publicado: (2022)

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial
por: Butler, Christopher C, et al.
Publicado: (2023)

Usual interstitial pneumonia
por: Badjate, Divya Manoj, et al.
Publicado: (2022)

Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial
por: Lawlor, Brian, et al.
Publicado: (2018)

The universe of ANA testing: a case for point-of-care ANA testing
por: Konstantinov, Konstantin N., et al.
Publicado: (2017)

Supervised exercise therapy versus usual care for patellofemoral pain syndrome: an open label randomised controlled trial
por: van Linschoten, R, et al.
Publicado: (2009)

Acenocoumarol Pharmacogenetic Dosing Algorithm versus Usual Care in Patients with Venous Thromboembolism: A Randomised Clinical Trial
por: Tong, Hoi Yan, et al.
Publicado: (2021)

Podiatry intervention versus usual care to prevent falls in care homes: pilot randomised controlled trial (the PIRFECT study)
por: Wylie, Gavin, et al.
Publicado: (2017)

The diabetes community exercise programme plus usual care versus usual care in patients with type 2 diabetes: A randomised, two-arm, parallel, open-label trial
por: Hale, L., et al.
Publicado: (2022)

Humanistic counselling plus pastoral care as usual versus pastoral care as usual for the treatment of psychological distress in adolescents in UK state schools (ETHOS): a randomised controlled trial
por: Cooper, Mick, et al.
Publicado: (2021)

Effectiveness, safety and economic viability of daycare versus usual hospital care management of severe pneumonia with or without malnutrition in children using the existing health system of Bangladesh: a cluster randomised controlled trial
por: Alam, Nur H., et al.
Publicado: (2023)

The DEVA trial: protocol for a randomised controlled trial of dequalinium chloride versus usual care antibiotics for the treatment of bacterial vaginosis
por: Haydock, Rebecca, et al.
Publicado: (2022)

The complete mitochondrial genome of Anas penelope (Anatidae: Anas)
por: Sun, Xiaoping, et al.
Publicado: (2020)

Anakinra after treatment with corticosteroids alone or with tocilizumab in patients with severe COVID-19 pneumonia and moderate hyperinflammation. A retrospective cohort study
por: Aomar-Millán, Ismael Francisco, et al.
Publicado: (2021)

The effectiveness of Stepping stones Triple P: the design of a randomised controlled trial on a parenting programme regarding children with mild intellectual disability and psychosocial problems versus care as usual
por: Kleefman, Marijke, et al.
Publicado: (2011)

Skin care education and individual counselling versus treatment as usual in healthcare workers with hand eczema: randomised clinical trial
por: Ibler, Kristina Sophie, et al.
Publicado: (2012)

Protocol for a feasibility randomised controlled trial of a musculoskeletal exercise intervention versus usual care for children with haemophilia
por: Hashem, Ferhana, et al.
Publicado: (2019)

Results of feasibility and safety of randomised controlled trial of a musculoskeletal exercise intervention versus usual care for children with haemophilia
por: Bladen, Melanie, et al.
Publicado: (2020)

The older prisoner health and social care assessment and plan (OHSCAP) versus treatment as usual: a randomised controlled trial
por: Forsyth, Katrina, et al.
Publicado: (2021)

Prone position versus usual care in hypoxemic COVID-19 patients in medical wards: a randomised controlled trial
por: Nay, Mai-Anh, et al.
Publicado: (2023)

Ana Karenina
por: Tolstoi, León, 1828-1910
Publicado: (1966)

Ana Karenina
por: Tolstoi, León, 1828-1910
Publicado: (2011)

Ana, soror--
por: Yourcenar, Marguerite, 1903-1987
Publicado: (1994)

Ana Karenina
por: Tolstoy, León, 1828-1910
Publicado: (1969)

Ana Bermejo
por: López Páez, Jorge, 1922-
Publicado: (1996)

Ana Bolena
por: Donizetti, Gaetano, 1797-1848
Publicado: (1878)

Effectiveness of antitussives, anticholinergics or honey versus usual care in adults with uncomplicated acute bronchitis: a study protocol of an open randomised clinical trial in primary care
por: Cots, Josep M, et al.
Publicado: (2019)

TELE-critical Care verSus usual Care On ICU PErformance (TELESCOPE): protocol for a cluster-randomised clinical trial on adult general ICUs in Brazil
por: Noritomi, Danilo Teixeira, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l6bdhtkt76g6149e16vf2lsabh