Heat inactivation of the severe acute respiratory syndrome coronavirus 2

Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respect...

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Detalles Bibliográficos
Autores principales: Batéjat, Christophe, Grassin, Quentin, Manuguerra, Jean-Claude, Leclercq, India
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825878/
https://www.ncbi.nlm.nih.gov/pubmed/33521591
http://dx.doi.org/10.1016/j.jobb.2020.12.001
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author Batéjat, Christophe
Grassin, Quentin
Manuguerra, Jean-Claude
Leclercq, India
author_facet Batéjat, Christophe
Grassin, Quentin
Manuguerra, Jean-Claude
Leclercq, India
author_sort Batéjat, Christophe
collection PubMed
description Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.
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spelling pubmed-78258782021-01-25 Heat inactivation of the severe acute respiratory syndrome coronavirus 2 Batéjat, Christophe Grassin, Quentin Manuguerra, Jean-Claude Leclercq, India J Biosaf Biosecur Short Communication Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions. Published by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. 2021-06 2021-01-23 /pmc/articles/PMC7825878/ /pubmed/33521591 http://dx.doi.org/10.1016/j.jobb.2020.12.001 Text en © 2021 Published by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Batéjat, Christophe
Grassin, Quentin
Manuguerra, Jean-Claude
Leclercq, India
Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title_full Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title_fullStr Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title_full_unstemmed Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title_short Heat inactivation of the severe acute respiratory syndrome coronavirus 2
title_sort heat inactivation of the severe acute respiratory syndrome coronavirus 2
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825878/
https://www.ncbi.nlm.nih.gov/pubmed/33521591
http://dx.doi.org/10.1016/j.jobb.2020.12.001
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