Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses: Implications for therapeutic strategies against SARS-CoV-2

Ion channels are necessary for correct lysosomal function including degradation of cargoes originating from endocytosis. Almost all enveloped viruses, including coronaviruses (CoVs), enter host cells via endocytosis, and do not escape endosomal compartments into the cytoplasm (via fusion with the en...

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Detalles Bibliográficos
Autores principales: Zhao, Zhuangzhuang, Qin, Pan, Huang, Yao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825922/
https://www.ncbi.nlm.nih.gov/pubmed/33516131
http://dx.doi.org/10.1016/j.ceca.2021.102360

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