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Pharmacoinformatics approach based identification of potential Nsp15 endoribonuclease modulators for SARS-CoV-2 inhibition
In the current study, a structure-based virtual screening paradigm was used to screen a small molecular database against the Non-structural protein 15 (Nsp15) endoribonuclease of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 is the causative agent of the recent outbrea...
Autores principales: | Savale, Rutuja Umesh, Bhowmick, Shovonlal, Osman, Sameh Mohamed, Alasmary, Fatmah Ali, Almutairi, Tahani Mazyad, Abdullah, Dalal Saied, Patil, Pritee Chunarkar, Islam, Md Ataul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825923/ https://www.ncbi.nlm.nih.gov/pubmed/33485847 http://dx.doi.org/10.1016/j.abb.2021.108771 |
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