Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid

A 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features...

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Detalles Bibliográficos
Autores principales: Takumida, Hiroshi, Izumi, Shinyu, Sakamoto, Keita, Hashimoto, Masao, Ishii, Satoru, Suzuki, Manabu, Takasaki, Jin, Tanaka, Mariko, Igari, Toru, Hojo, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Respiratory Society. Published by Elsevier B.V. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825973/
https://www.ncbi.nlm.nih.gov/pubmed/33547007
http://dx.doi.org/10.1016/j.resinv.2020.12.005
Descripción
Sumario:A 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features of organizing pneumonia with alveolar epithelial injury, and prednisolone administration led to alleviation of respiratory symptoms and recovery of respiratory function. This case report is the first to demonstrate the use of corticosteroids to successfully treat post-COVID-19 respiratory failure in a patient with biopsy-proven organizing pneumonia. We propose that steroid treatment be considered for patients with persistent respiratory dysfunction as COVID-19 pneumonia sequelae.

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