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Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Virus-specific humoral and cellular immunity act synergistically to protect the host from viral infection. We interrogate the dynamic changes of virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infection from disease onset to convalescence or death. We quanti...
Autores principales: | Tan, Anthony T., Linster, Martin, Tan, Chee Wah, Le Bert, Nina, Chia, Wan Ni, Kunasegaran, Kamini, Zhuang, Yan, Tham, Christine Y.L., Chia, Adeline, Smith, Gavin J.D., Young, Barnaby, Kalimuddin, Shirin, Low, Jenny G.H., Lye, David, Wang, Lin-Fa, Bertoletti, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826084/ https://www.ncbi.nlm.nih.gov/pubmed/33516277 http://dx.doi.org/10.1016/j.celrep.2021.108728 |
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