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COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection
The novel coronavirus (COVID-19) outbreak emerged in December 2019. The disease has caused loss of many lives and has become an unprecedented threat to public health worldwide. We develop simple COVID-19 epidemic models to study treatment strategies to control the pandemic. The results show that era...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826112/ https://www.ncbi.nlm.nih.gov/pubmed/33521408 http://dx.doi.org/10.1016/j.idm.2021.01.007 |
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author | Oduro, Bismark Magagula, Vusi Mpendulo |
author_facet | Oduro, Bismark Magagula, Vusi Mpendulo |
author_sort | Oduro, Bismark |
collection | PubMed |
description | The novel coronavirus (COVID-19) outbreak emerged in December 2019. The disease has caused loss of many lives and has become an unprecedented threat to public health worldwide. We develop simple COVID-19 epidemic models to study treatment strategies to control the pandemic. The results show that eradication of the disease is possible if the efficacy of treatment is perfect. We also investigate the existence of a dual-rate effect. Conditions under which the effect occurs are derived. When the effect is present, a tactic to control the infection might be to initially treat infected individuals aggressively at a relatively high rate to drive the prevalence to a lower region that can be maintained in the long run at relatively moderate rate and cost. |
format | Online Article Text |
id | pubmed-7826112 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-78261122021-01-25 COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection Oduro, Bismark Magagula, Vusi Mpendulo Infect Dis Model Special issue on Modelling and Forecasting the 2019 Novel Coronavirus (2019-nCoV) Transmission; Edited by Prof. Carlos Castillo-Chavez, Prof. Gerardo Chowell-Puente, Prof. Ping Yan, Prof. Jianhong Wu The novel coronavirus (COVID-19) outbreak emerged in December 2019. The disease has caused loss of many lives and has become an unprecedented threat to public health worldwide. We develop simple COVID-19 epidemic models to study treatment strategies to control the pandemic. The results show that eradication of the disease is possible if the efficacy of treatment is perfect. We also investigate the existence of a dual-rate effect. Conditions under which the effect occurs are derived. When the effect is present, a tactic to control the infection might be to initially treat infected individuals aggressively at a relatively high rate to drive the prevalence to a lower region that can be maintained in the long run at relatively moderate rate and cost. KeAi Publishing 2021-01-23 /pmc/articles/PMC7826112/ /pubmed/33521408 http://dx.doi.org/10.1016/j.idm.2021.01.007 Text en © 2021 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Special issue on Modelling and Forecasting the 2019 Novel Coronavirus (2019-nCoV) Transmission; Edited by Prof. Carlos Castillo-Chavez, Prof. Gerardo Chowell-Puente, Prof. Ping Yan, Prof. Jianhong Wu Oduro, Bismark Magagula, Vusi Mpendulo COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title | COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title_full | COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title_fullStr | COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title_full_unstemmed | COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title_short | COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection |
title_sort | covid-19 intervention models: an initial aggressive treatment strategy for controlling the infection |
topic | Special issue on Modelling and Forecasting the 2019 Novel Coronavirus (2019-nCoV) Transmission; Edited by Prof. Carlos Castillo-Chavez, Prof. Gerardo Chowell-Puente, Prof. Ping Yan, Prof. Jianhong Wu |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826112/ https://www.ncbi.nlm.nih.gov/pubmed/33521408 http://dx.doi.org/10.1016/j.idm.2021.01.007 |
work_keys_str_mv | AT odurobismark covid19interventionmodelsaninitialaggressivetreatmentstrategyforcontrollingtheinfection AT magagulavusimpendulo covid19interventionmodelsaninitialaggressivetreatmentstrategyforcontrollingtheinfection |