Cargando…

What do we know about the antibody responses to SARS-CoV-2?

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lagunas-Rangel, Francisco Alejandro, Chávez-Valencia, Venice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826124/
https://www.ncbi.nlm.nih.gov/pubmed/33524881
http://dx.doi.org/10.1016/j.imbio.2021.152054
_version_ 1783640467664011264
author Lagunas-Rangel, Francisco Alejandro
Chávez-Valencia, Venice
author_facet Lagunas-Rangel, Francisco Alejandro
Chávez-Valencia, Venice
author_sort Lagunas-Rangel, Francisco Alejandro
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of the adaptive immune response, to develop vaccines and therapies, we must understand the antibody response to SARS-CoV-2 infection. In this work, we summarize the most important findings of antibody-mediated immunity against SARS-CoV-2 and highlight its role in the efficient use of plasma from convalescent patients and the direct application of antibodies as treatment.
format Online
Article
Text
id pubmed-7826124
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier GmbH.
record_format MEDLINE/PubMed
spelling pubmed-78261242021-01-25 What do we know about the antibody responses to SARS-CoV-2? Lagunas-Rangel, Francisco Alejandro Chávez-Valencia, Venice Immunobiology Review Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of the adaptive immune response, to develop vaccines and therapies, we must understand the antibody response to SARS-CoV-2 infection. In this work, we summarize the most important findings of antibody-mediated immunity against SARS-CoV-2 and highlight its role in the efficient use of plasma from convalescent patients and the direct application of antibodies as treatment. Elsevier GmbH. 2021-03 2021-01-23 /pmc/articles/PMC7826124/ /pubmed/33524881 http://dx.doi.org/10.1016/j.imbio.2021.152054 Text en © 2021 Elsevier GmbH. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Lagunas-Rangel, Francisco Alejandro
Chávez-Valencia, Venice
What do we know about the antibody responses to SARS-CoV-2?
title What do we know about the antibody responses to SARS-CoV-2?
title_full What do we know about the antibody responses to SARS-CoV-2?
title_fullStr What do we know about the antibody responses to SARS-CoV-2?
title_full_unstemmed What do we know about the antibody responses to SARS-CoV-2?
title_short What do we know about the antibody responses to SARS-CoV-2?
title_sort what do we know about the antibody responses to sars-cov-2?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826124/
https://www.ncbi.nlm.nih.gov/pubmed/33524881
http://dx.doi.org/10.1016/j.imbio.2021.152054
work_keys_str_mv AT lagunasrangelfranciscoalejandro whatdoweknowabouttheantibodyresponsestosarscov2
AT chavezvalenciavenice whatdoweknowabouttheantibodyresponsestosarscov2