Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites

An abnormally high rate of UV-light related mutations appears at transcription factor binding sites (TFBS) across melanomas. The binding of transcription factors (TFs) to the DNA impairs the repair of UV-induced lesions and certain TFs have been shown to increase the rate of generation of these lesi...

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Detalles Bibliográficos
Autores principales: Frigola, Joan, Sabarinathan, Radhakrishnan, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826277/
https://www.ncbi.nlm.nih.gov/pubmed/33347579
http://dx.doi.org/10.1093/nar/gkaa1219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826277/
https://www.ncbi.nlm.nih.gov/pubmed/33347579
http://dx.doi.org/10.1093/nar/gkaa1219

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