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Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites
An abnormally high rate of UV-light related mutations appears at transcription factor binding sites (TFBS) across melanomas. The binding of transcription factors (TFs) to the DNA impairs the repair of UV-induced lesions and certain TFs have been shown to increase the rate of generation of these lesi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826277/ https://www.ncbi.nlm.nih.gov/pubmed/33347579 http://dx.doi.org/10.1093/nar/gkaa1219 |