Cargando…
Prevalence of HPV infections in surgical smoke exposed gynecologists
OBJECTIVES: Human papillomavirus (HPV) has been reported recently in surgical smoke generated by gynecological operations. The objective of this study was to investigate whether gynecologists who have performed electrosurgery including loop electrosurgical excision procedure (LEEP), are at risk of a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826298/ https://www.ncbi.nlm.nih.gov/pubmed/32870342 http://dx.doi.org/10.1007/s00420-020-01568-9 |
_version_ | 1783640506918502400 |
---|---|
author | Hu, Xiaoli Zhou, Qingfeng Yu, Jian Wang, Jing Tu, Quanmei Zhu, Xueqiong |
author_facet | Hu, Xiaoli Zhou, Qingfeng Yu, Jian Wang, Jing Tu, Quanmei Zhu, Xueqiong |
author_sort | Hu, Xiaoli |
collection | PubMed |
description | OBJECTIVES: Human papillomavirus (HPV) has been reported recently in surgical smoke generated by gynecological operations. The objective of this study was to investigate whether gynecologists who have performed electrosurgery including loop electrosurgical excision procedure (LEEP), are at risk of acquiring HPV DNA through surgical smoke. METHODS: A related questionnaire was designed and 700 gynecologist nasal swab samples were collected in 67 hospitals. In addition, the flow fluorescence hybridization technique was used to detect HPV DNA, and the Chi-square test was applied to analyze whether related risk factors including electrical surgery, were correlated with HPV infection in surgeons’ nasal epithelial cells. RESULTS: The HPV infection rate in the nasal epithelial cells of the participants who performed electrosurgery (8.96%, 42/469) or LEEP (10.11%, 36/356) was significantly higher than that in the remaining participants who did not perform electrosurgery (1.73%, 4/231) or LEEP (2.91%, 10/344), respectively. The most prevalent HPV genotype in the electrosurgery group was HPV16 (76.19%, 32/42). The HPV-positive rate was increased in the group that had a longer duration of electrosurgery (P = 0.016). Additionally, the HPV detection rate was significantly lower in electrosurgery operators who used surgical mask (7.64%, 33/432) than in those who did not use protective masks (24.32%, 9/37). Furthermore, the N95 mask (0%, 0/196) significantly reduced the risk for HPV infection compared to that with the general mask (13.98%, 33/236, P < 0.001). Furthermore, 46 participants infected with HPV were followed-up for 3–24 months, and approximately 43.48% (20/46) and 100% (41/41) became negative for HPV DNA, respectively. CONCLUSIONS: Gynecologists who performed electrosurgery including LEEP were at risk of acquiring HPV infection. Surgical masks, especially the N95 mask, significantly decreased the hazard of HPV transmission from surgical smoke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00420-020-01568-9) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-7826298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-78262982021-02-11 Prevalence of HPV infections in surgical smoke exposed gynecologists Hu, Xiaoli Zhou, Qingfeng Yu, Jian Wang, Jing Tu, Quanmei Zhu, Xueqiong Int Arch Occup Environ Health Original Article OBJECTIVES: Human papillomavirus (HPV) has been reported recently in surgical smoke generated by gynecological operations. The objective of this study was to investigate whether gynecologists who have performed electrosurgery including loop electrosurgical excision procedure (LEEP), are at risk of acquiring HPV DNA through surgical smoke. METHODS: A related questionnaire was designed and 700 gynecologist nasal swab samples were collected in 67 hospitals. In addition, the flow fluorescence hybridization technique was used to detect HPV DNA, and the Chi-square test was applied to analyze whether related risk factors including electrical surgery, were correlated with HPV infection in surgeons’ nasal epithelial cells. RESULTS: The HPV infection rate in the nasal epithelial cells of the participants who performed electrosurgery (8.96%, 42/469) or LEEP (10.11%, 36/356) was significantly higher than that in the remaining participants who did not perform electrosurgery (1.73%, 4/231) or LEEP (2.91%, 10/344), respectively. The most prevalent HPV genotype in the electrosurgery group was HPV16 (76.19%, 32/42). The HPV-positive rate was increased in the group that had a longer duration of electrosurgery (P = 0.016). Additionally, the HPV detection rate was significantly lower in electrosurgery operators who used surgical mask (7.64%, 33/432) than in those who did not use protective masks (24.32%, 9/37). Furthermore, the N95 mask (0%, 0/196) significantly reduced the risk for HPV infection compared to that with the general mask (13.98%, 33/236, P < 0.001). Furthermore, 46 participants infected with HPV were followed-up for 3–24 months, and approximately 43.48% (20/46) and 100% (41/41) became negative for HPV DNA, respectively. CONCLUSIONS: Gynecologists who performed electrosurgery including LEEP were at risk of acquiring HPV infection. Surgical masks, especially the N95 mask, significantly decreased the hazard of HPV transmission from surgical smoke. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00420-020-01568-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-09-01 2021 /pmc/articles/PMC7826298/ /pubmed/32870342 http://dx.doi.org/10.1007/s00420-020-01568-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Article Hu, Xiaoli Zhou, Qingfeng Yu, Jian Wang, Jing Tu, Quanmei Zhu, Xueqiong Prevalence of HPV infections in surgical smoke exposed gynecologists |
title | Prevalence of HPV infections in surgical smoke exposed gynecologists |
title_full | Prevalence of HPV infections in surgical smoke exposed gynecologists |
title_fullStr | Prevalence of HPV infections in surgical smoke exposed gynecologists |
title_full_unstemmed | Prevalence of HPV infections in surgical smoke exposed gynecologists |
title_short | Prevalence of HPV infections in surgical smoke exposed gynecologists |
title_sort | prevalence of hpv infections in surgical smoke exposed gynecologists |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826298/ https://www.ncbi.nlm.nih.gov/pubmed/32870342 http://dx.doi.org/10.1007/s00420-020-01568-9 |
work_keys_str_mv | AT huxiaoli prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists AT zhouqingfeng prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists AT yujian prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists AT wangjing prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists AT tuquanmei prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists AT zhuxueqiong prevalenceofhpvinfectionsinsurgicalsmokeexposedgynecologists |