Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V)1.5‐mediated EMT and FAK/Paxillin signaling pathway

Lidocaine, one of the most commonly used local anesthetics during surgery, has been reported to suppress cancer cell growth via blocking voltage‐gated sodium channels (VGSCs). VGSC 1.5 (Na(V)1.5) is highly expressed in invasive cancers including ovarian cancer. This study aims to investigate whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chang, Yu, Ming, Li, Yi, Wang, Hao, Xu, Chuanya, Zhang, Xiaoqing, Li, Min, Guo, Hongyan, Ma, Daqing, Guo, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826465/
https://www.ncbi.nlm.nih.gov/pubmed/33280262
http://dx.doi.org/10.1002/cam4.3621

Ejemplares similares

Ejemplares similares