Cargando…

Screening of potent drug inhibitors against SARS-CoV-2 RNA polymerase: an in silico approach

COVID-19 has emerged as a rapidly escalating serious global health issue, affecting every section of population in a detrimental way. Present situation invigorated researchers to look for potent targets, development as well as repurposing of conventional therapeutic drugs. NSP12, a RNA polymerase, i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Sanjay Kumar, Upadhyay, Atul Kumar, Reddy, M. Sudhakara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826501/ https://www.ncbi.nlm.nih.gov/pubmed/33520579 http://dx.doi.org/10.1007/s13205-020-02610-w

Ejemplares similares

In silico identification of promising inhibitor against RNA-dependent RNA polymerase target of SARS-CoV-2
por: Singh, Pushpendra, et al.
Publicado: (2021)

Drummondin E and Flinderole B are potential inhibitors of RNA-dependent RNA polymerase of SARS-CoV-2: an in silico study
por: Akhtar, Nahid, et al.
Publicado: (2022)

Identification of FDA approved drugs and nucleoside analogues as potential SARS-CoV-2 A1pp domain inhibitor: An in silico study
por: Singh, Atul Kumar, et al.
Publicado: (2021)

Marine drugs as putative inhibitors against non-structural proteins of SARS-CoV-2: an in silico study
por: Patel, Simran, et al.
Publicado: (2023)

Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2
por: Tripathi, Praveen Kumar, et al.
Publicado: (2020)

In silico analysis of Phyllanthus amarus phytochemicals as potent drugs against SARS-CoV-2 main protease
por: Murthy, T.P. Krishna, et al.
Publicado: (2021)

Potential of turmeric-derived compounds against RNA‐dependent RNA polymerase of SARS‐CoV‐2: An in-silico approach
por: Singh, Rahul, et al.
Publicado: (2021)

Identification of potent compounds against SARs-CoV-2: An in-silico based drug searching against Mpro
por: Hassam, Muhammad, et al.
Publicado: (2022)

Phytoconstituents from ten natural herbs as potent inhibitors of main protease enzyme of SARS-COV-2: In silico study
por: Kumar, Nitish, et al.
Publicado: (2021)

Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2
por: Bhardwaj, Vijay Kumar, et al.
Publicado: (2021)

Discovering Potential RNA Dependent RNA Polymerase Inhibitors as Prospective Drugs Against COVID-19: An in silico Approach
por: Saha, Satabdi, et al.
Publicado: (2021)

In silico evaluation of potential intervention against SARS-CoV-2 RNA-dependent RNA polymerase
por: Kapoor, Shreya, et al.
Publicado: (2023)

Screening of Potent Phytochemical Inhibitors Against SARS-CoV-2 Main Protease: An Integrative Computational Approach
por: Mahmud, Shafi, et al.
Publicado: (2021)

In silico screening of potent inhibitors against COVID-19 key targets from a library of FDA-approved drugs
por: Elmorsy, Mohammad A., et al.
Publicado: (2021)

In-silico evaluation of bioactive compounds from tea as potential SARS-CoV-2 nonstructural protein 16 inhibitors
por: Singh, Rahul, et al.
Publicado: (2021)

In Silico Screening of the DrugBank Database to Search for Possible Drugs against SARS-CoV-2
por: Cuesta, Sebastián A., et al.
Publicado: (2021)

In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs
por: Mondal, Sunil Kanti, et al.
Publicado: (2021)

Drug repurposing for identification of potential inhibitors against SARS-CoV-2 spike receptor-binding domain: An in silico approach
por: Behera, Santosh Kumar, et al.
Publicado: (2021)

Nucleotide analogues as inhibitors of SARS‐CoV Polymerase
por: Ju, Jingyue, et al.
Publicado: (2020)

Repurposing nonnucleoside antivirals against SARS-CoV2 NSP12 (RNA dependent RNA polymerase): In silico-molecular insight
por: Begum, Feroza, et al.
Publicado: (2021)

Combining SARS-CoV-2 Proofreading Exonuclease and RNA-Dependent RNA Polymerase Inhibitors as a Strategy to Combat COVID-19: A High-Throughput in silico Screening
por: Khater, Shradha, et al.
Publicado: (2021)

Design of a multi-epitope vaccine against the pathogenic fungi Candida tropicalis using an in silico approach
por: Akhtar, Nahid, et al.
Publicado: (2022)

Discovery of a Natural Product with Potent Efficacy Against SARS-CoV-2 by Drug Screening
por: Li, Daixi, et al.
Publicado: (2021)

Investigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach
por: Singh, Sanjay Kumar, et al.
Publicado: (2019)

In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy
por: Wei, Tian-zi, et al.
Publicado: (2020)

In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease
por: Yañez, Osvaldo, et al.
Publicado: (2021)

Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants
por: Muhammad, Ijaz, et al.
Publicado: (2021)

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase
por: Chien, Minchen, et al.
Publicado: (2020)

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
por: Neogi, Ujjwal, et al.
Publicado: (2020)

An in-silico evaluation of different bioactive molecules of tea for their inhibition potency against non structural protein-15 of SARS-CoV-2
por: Sharma, Jatin, et al.
Publicado: (2021)

Recent updates on the biological efficacy of approved drugs and potent synthetic compounds against SARS-CoV-2
por: Anjani,, et al.
Publicado: (2023)

In-silico design of a potential inhibitor of SARS-CoV-2 S protein
por: Jaiswal, Grijesh, et al.
Publicado: (2020)

Potential of Marine Terpenoids against SARS-CoV-2: An In Silico Drug Development Approach
por: Sahoo, Alaka, et al.
Publicado: (2021)

In-silico screening and in-vitro assay show the antiviral effect of Indomethacin against SARS-CoV-2
por: Chakraborty, Rajkumar, et al.
Publicado: (2022)

Exploration of In-silico screening of therapeutic agents against SARS-CoV-2
por: Thakur, Yamini, et al.
Publicado: (2021)

In-Silico Screening and Molecular Dynamics Simulation of Drug Bank Experimental Compounds against SARS-CoV-2
por: Alturki, Norah A., et al.
Publicado: (2022)

Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective
por: Sonousi, Amr, et al.
Publicado: (2021)

In silico prediction of potential inhibitors for the main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing
por: Kumar, Yogesh, et al.
Publicado: (2020)

Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
por: Garcia, Gustavo, et al.
Publicado: (2021)

Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19
por: Baby, Krishnaprasad, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5uccma3ucvpg0bfehv8fu1tgfe