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Nuclear Localization of Heme Oxygenase-1 in Pathophysiological Conditions: Does It Explain the Dual Role in Cancer?

Heme Oxygenase-1 (HO-1) is a type II detoxifying enzyme that catalyzes the rate-limiting step in heme degradation leading to the formation of equimolar quantities of carbon monoxide (CO), free iron and biliverdin. HO-1 was originally shown to localize at the smooth endoplasmic reticulum membrane (sE...

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Detalles Bibliográficos
Autores principales:	Mascaró, Marilina, Alonso, Eliana N., Alonso, Exequiel G., Lacunza, Ezequiel, Curino, Alejandro C., Facchinetti, María Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826503/ https://www.ncbi.nlm.nih.gov/pubmed/33440611 http://dx.doi.org/10.3390/antiox10010087

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