Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory

There are two molecular processes that are essential for living bodies to maintain their life: the molecular recognition, and the self-organization or self-assembly. Binding of a substrate by an enzyme is an example of the molecular recognition, while the protein folding is a good example of the sel...

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Autores principales: Sugita, Masatake, Onishi, Itaru, Irisa, Masayuki, Yoshida, Norio, Hirata, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826681/
https://www.ncbi.nlm.nih.gov/pubmed/33430461
http://dx.doi.org/10.3390/molecules26020271
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author Sugita, Masatake
Onishi, Itaru
Irisa, Masayuki
Yoshida, Norio
Hirata, Fumio
author_facet Sugita, Masatake
Onishi, Itaru
Irisa, Masayuki
Yoshida, Norio
Hirata, Fumio
author_sort Sugita, Masatake
collection PubMed
description There are two molecular processes that are essential for living bodies to maintain their life: the molecular recognition, and the self-organization or self-assembly. Binding of a substrate by an enzyme is an example of the molecular recognition, while the protein folding is a good example of the self-organization process. The two processes are further governed by the other two physicochemical processes: solvation and the structural fluctuation. In the present article, the studies concerning the two molecular processes carried out by Hirata and his coworkers, based on the statistical mechanics of molecular liquids or the RISM/3D-RISM theory, are reviewed.
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spelling pubmed-78266812021-01-25 Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory Sugita, Masatake Onishi, Itaru Irisa, Masayuki Yoshida, Norio Hirata, Fumio Molecules Review There are two molecular processes that are essential for living bodies to maintain their life: the molecular recognition, and the self-organization or self-assembly. Binding of a substrate by an enzyme is an example of the molecular recognition, while the protein folding is a good example of the self-organization process. The two processes are further governed by the other two physicochemical processes: solvation and the structural fluctuation. In the present article, the studies concerning the two molecular processes carried out by Hirata and his coworkers, based on the statistical mechanics of molecular liquids or the RISM/3D-RISM theory, are reviewed. MDPI 2021-01-07 /pmc/articles/PMC7826681/ /pubmed/33430461 http://dx.doi.org/10.3390/molecules26020271 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sugita, Masatake
Onishi, Itaru
Irisa, Masayuki
Yoshida, Norio
Hirata, Fumio
Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title_full Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title_fullStr Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title_full_unstemmed Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title_short Molecular Recognition and Self-Organization in Life Phenomena Studied by a Statistical Mechanics of Molecular Liquids, the RISM/3D-RISM Theory
title_sort molecular recognition and self-organization in life phenomena studied by a statistical mechanics of molecular liquids, the rism/3d-rism theory
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826681/
https://www.ncbi.nlm.nih.gov/pubmed/33430461
http://dx.doi.org/10.3390/molecules26020271
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