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Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers
Platinum resistance seriously impacts on the survival outcomes of patients with ovarian cancers. Platinum-induced DNA damage is processed through DNA repair. NBS1 is a key DNA repair protein. Here, we evaluated the role of NBS1 in ovarian cancers. NBS1 expression was investigated in clinical cohorts...
Autores principales: | Alblihy, Adel, Alabdullah, Muslim L., Ali, Reem, Algethami, Mashael, Toss, Michael S., Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826685/ https://www.ncbi.nlm.nih.gov/pubmed/33435622 http://dx.doi.org/10.3390/biomedicines9010056 |
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