Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest

Less toxic treatment strategies for testicular germ cell tumor (TGCT) patients are needed, as overtreatment is a concern due to the long-term side effects of platin-based chemotherapy. Although clinical benefit from classical hypomethylating agents has to date been limited, TGCTs show an abnormal DN...

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Detalles Bibliográficos
Autores principales: Lobo, João, Cardoso, Ana Rita, Miranda-Gonçalves, Vera, Looijenga, Leendert H. J., Lopez, Marie, Arimondo, Paola B., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826804/
https://www.ncbi.nlm.nih.gov/pubmed/33430420
http://dx.doi.org/10.3390/pharmaceutics13010073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826804/
https://www.ncbi.nlm.nih.gov/pubmed/33430420
http://dx.doi.org/10.3390/pharmaceutics13010073

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