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Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells
The implementation of chemo- and bioinformatics tools is a crucial step in the design of structure-based drugs, enabling the identification of more specific and effective molecules against cancer without side effects. In this study, three new compounds were designed and synthesized with suitable abs...
Autores principales: | Méndez-Luna, David, Morelos-Garnica, Loreley Araceli, García-Vázquez, Juan Benjamín, Bello, Martiniano, Padilla-Martínez, Itzia Irene, Fragoso-Vázquez, Manuel Jonathan, Dueñas González, Alfonso, De Pedro, Nuria, Gómez-Vidal, José Antonio, Mendoza-Figueroa, Humberto Lubriel, Correa-Basurto, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826836/ https://www.ncbi.nlm.nih.gov/pubmed/33435260 http://dx.doi.org/10.3390/ph14010049 |
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