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Neuron–Glia Interactions in Tuberous Sclerosis Complex Affect the Synaptic Balance in 2D and Organoid Cultures

Tuberous sclerosis complex (TSC) is a genetic disease affecting the brain. Neurological symptoms like epilepsy and neurodevelopmental issues cause a significant burden on patients. Both neurons and glial cells are affected by TSC mutations. Previous studies have shown changes in the excitation/inhib...

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Detalles Bibliográficos
Autores principales: Dooves, Stephanie, van Velthoven, Arianne J. H., Suciati, Linda G., Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826837/
https://www.ncbi.nlm.nih.gov/pubmed/33445520
http://dx.doi.org/10.3390/cells10010134

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