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A Modelling Framework Linking Resource-Based Stochastic Translation to the Optimal Design of Synthetic Constructs

SIMPLE SUMMARY: In synthetic biology, it is commonplace to design and insert gene expression constructs into cells for the production of useful proteins. In order to maximise production yield, it is useful to predict the performance of these “engineered cells” in advance of conducting experiments. T...

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Detalles Bibliográficos
Autores principales: Sarvari, Peter, Ingram, Duncan, Stan, Guy-Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826857/
https://www.ncbi.nlm.nih.gov/pubmed/33430483
http://dx.doi.org/10.3390/biology10010037