Cargando…

Improvement Effect of Metformin on Female and Male Reproduction in Endocrine Pathologies and Its Mechanisms

Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in combination with other drugs, restores the ovarian function in women with polycystic ovary syndrome (PCOS) and improves fetal development, pregnancy outcomes and offspring health in gestational diabetes mellitus...

Descripción completa

Detalles Bibliográficos
Autor principal:	Shpakov, Alexander O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826885/ https://www.ncbi.nlm.nih.gov/pubmed/33429918 http://dx.doi.org/10.3390/ph14010042

Ejemplares similares

Endocrine‐disrupting chemicals and male reproductive health
por: Sharma, Aditi, et al.
Publicado: (2020)

The Effect of Metformin on Male Reproductive Function and Prostate: An Updated Review
por: Tseng, Chin-Hsiao
Publicado: (2022)

Role of Endocrine System in the Regulation of Female Insect Reproduction
por: Khalid, Muhammad Zaryab, et al.
Publicado: (2021)

Endocrine disrupting chemicals and impact on male reproductive health
por: Rehman, Saba, et al.
Publicado: (2018)

The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect
por: Derkach, Kira, et al.
Publicado: (2019)

Transgenerational Effects of Prenatal Endocrine Disruption on Reproductive and Sociosexual Behaviors in Sprague Dawley Male and Female Rats
por: Kermath, Bailey A., et al.
Publicado: (2022)

Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction
por: Gregoraszczuk, Ewa L., et al.
Publicado: (2013)

Ghrelin in Female and Male Reproduction
por: Dupont, Joëlle, et al.
Publicado: (2010)

Hot Spots for the Use of Intranasal Insulin: Cerebral Ischemia, Brain Injury, Diabetes Mellitus, Endocrine Disorders and Postoperative Delirium
por: Shpakov, Alexander O., et al.
Publicado: (2023)

MicroRNAs: potential targets and agents of endocrine disruption in female reproduction
por: Sabry, Reem, et al.
Publicado: (2019)

Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-Induced Polycystic Ovarian Syndrome With Insulin Resistance
por: Xie, Yidong, et al.
Publicado: (2021)

Brain Control Reproduction by the Endocrine System of Female Blue Gourami (Trichogaster trichopterus)
por: Degani, Gad
Publicado: (2020)

Black Elder and Its Constituents: Molecular Mechanisms of Action Associated with Female Reproduction
por: Kolesarova, Adriana, et al.
Publicado: (2022)

Low energy availability: history, definition and evidence of its endocrine, metabolic and physiological effects in prospective studies in females and males
por: Areta, José L., et al.
Publicado: (2020)

Immune-Endocrine Cross-Talk in Reproductive Biology and Pathology
por: Galvão, António M., et al.
Publicado: (2014)

Exposure to Endocrine Disrupting Chemicals and Male Reproductive Health
por: Jeng, Hueiwang Anna
Publicado: (2014)

Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands
por: Shpakov, Alexander O.
Publicado: (2023)

Endocrine Disruptors in Water and Their Effects on the Reproductive System
por: Gonsioroski, Andressa, et al.
Publicado: (2020)

The Role of Nitric Oxide on Male and Female Reproduction
por: DUTTA, Sulagna, et al.
Publicado: (2022)

Tissue-resident immunity in the female and male reproductive tract
por: Yüzen, Dennis, et al.
Publicado: (2022)

Role of endocrine disruptors in male infertility and impact of COVID-19 on male reproduction
por: Panner Selvam, Manesh Kumar, et al.
Publicado: (2022)

Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substances
por: Auger, Jacques, et al.
Publicado: (2014)

Male reproductive health as a sentinel for environmental endocrine disruption
por: Toppari, Jorma
Publicado: (2012)

Endocrine Pathology of the Ovary
por: Ober, William B.
Publicado: (1958)

The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone Receptor on Steroidogenesis and Spermatogenesis
por: Bakhtyukov, Andrey A., et al.
Publicado: (2021)

Mechanisms of Male Reproductive Toxicity of Polybrominated Diphenyl Ethers
por: Arowolo, Olatunbosun, et al.
Publicado: (2022)

Seminal Fluid-Mediated Inflammation in Physiology and Pathology of the Female Reproductive Tract
por: Adefuye, Anthonio O., et al.
Publicado: (2016)

Reactive Nitrogen Species and Male Reproduction: Physiological and Pathological Aspects
por: Dutta, Sulagna, et al.
Publicado: (2022)

Leptin and its actions on reproduction in males
por: Malik, Ifrah Alam, et al.
Publicado: (2019)

Biology and physiology of Calbindin-D9k in female reproductive tissues: Involvement of steroids and endocrine disruptors
por: Choi, Kyung-Chul, et al.
Publicado: (2005)

Shiftwork and Light at Night Negatively Impact Molecular and Endocrine Timekeeping in the Female Reproductive Axis in Humans and Rodents
por: Yaw, Alexandra M., et al.
Publicado: (2020)

Impact of Triclosan on Female and Male Reproductive System and Its Consequences on Fertility: A Literature Review
por: Maksymowicz, Marcela, et al.
Publicado: (2022)

PCBs Are Endocrine Disruptors: Mixture Affects Reproductive Development in Female Mice
por: McGovern, Victoria
Publicado: (2006)

Metformin Exposure at Environmentally Relevant Concentrations Causes Potential Endocrine Disruption in Adult Male Fish
por: Niemuth, Nicholas J, et al.
Publicado: (2015)

Effects of crocin and metformin on methylglyoxal-induced reproductive system dysfunction in diabetic male mice
por: Kheirollahi Khorasani, Maryam, et al.
Publicado: (2021)

Are epigenetic mechanisms and nutrition effective in male and female infertility?
por: Erdoğan, Kadriye, et al.
Publicado: (2023)

The Relevance of Aquaporins for the Physiology, Pathology, and Aging of the Female Reproductive System in Mammals
por: Kordowitzki, Paweł, et al.
Publicado: (2020)

Alterations of the male and female reproductive systems induced by COVID-19
por: Carneiro Gomes, Paulo Roberto, et al.
Publicado: (2021)

Targeting Aquaporins in Novel Therapies for Male and Female Breast and Reproductive Cancers
por: Khan, Sidra, et al.
Publicado: (2021)

Endocrine management of male subfertility
por: George, Belinda, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_u1kg293m0rcdg02mc3hd2q9bbs