Cargando…

Circulating Total Cell-Free DNA Levels Are Increased in Hypertensive Disorders of Pregnancy and Associated with Prohypertensive Factors and Adverse Clinical Outcomes

Previous studies have described increased circulating cell-free DNA (cfDNA) in hypertensive disorders of pregnancy (HDP). Here, we aimed first to confirm this information using a simple, but sensible fluorescent assay, and second to investigate whether total cfDNA is associated with circulating fact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amaral, Lorena M., Sandrim, Valeria C., Kutcher, Matthew E., Spradley, Frank T., Cavalli, Ricardo C., Tanus-Santos, Jose E., Palei, Ana C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826953/ https://www.ncbi.nlm.nih.gov/pubmed/33429954 http://dx.doi.org/10.3390/ijms22020564

Ejemplares similares

Hypertension and Prohypertensive Antineoplastic Therapies in Cancer Patients
por: van Dorst, Daan C.H., et al.
Publicado: (2021)

Plasma eNOS Concentration in Healthy Pregnancy and in Hypertensive Disorders of Pregnancy: Evidence of Reduced Concentrations in Pre-Eclampsia from Two Independent Studies
por: Kaihara, Julyane N. S., et al.
Publicado: (2023)

Circulating Tissue Inhibitor of Metalloproteinase-4 levels are not a Predictor of Preeclampsia in the period between 20 and 25 Weeks of Gestation
por: Sandrim, Valeria Cristina, et al.
Publicado: (2018)

Obese melanocortin-4 receptor-deficient rats exhibit augmented angiogenic balance and vasorelaxation during pregnancy
por: Spradley, Frank T, et al.
Publicado: (2013)

Human pulmonary artery endothelial cells in the model of mucopolysaccharidosis VI present a prohypertensive phenotype
por: Golda, Adam, et al.
Publicado: (2015)

Plasma from pre‐eclamptic patients induces the expression of the anti‐angiogenic miR‐195‐5p in endothelial cells
por: Sandrim, Valeria Cristina, et al.
Publicado: (2016)

Preeclampsia and Gestational Hypertension: Biochemical and Antioxidant Features in Vitro Might Help Understand Different Outcomes
por: Galvão, Victoria Elizabeth, et al.
Publicado: (2021)

Immune Mechanisms Linking Obesity and Preeclampsia
por: Spradley, Frank T., et al.
Publicado: (2015)

Placental Ischemia Says “NO” to Proper NOS-Mediated Control of Vascular Tone and Blood Pressure in Preeclampsia
por: Palei, Ana C., et al.
Publicado: (2021)

Polymorphisms and Haplotypes in Candidate Genes Related to Angiogenesis and Endothelial Dysfunction in Preeclampsia
por: Luizon, Marcelo Rizzatti, et al.
Publicado: (2012)

Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre-eclampsia
por: Amaral, Lorena M, et al.
Publicado: (2013)

Circulating Heme Oxygenase-1: Not a Predictor of Preeclampsia but Highly Expressed in Pregnant Women Who Subsequently Develop Severe Preeclampsia
por: Sandrim, Valéria C., et al.
Publicado: (2018)

Prohypertensive Effect of Gestational Personal Exposure to Fine Particulate Matter. Prospective Cohort Study in Non-smoking and Non-obese Pregnant Women
por: Jedrychowski, Wieslaw A., et al.
Publicado: (2012)

Circulating MicroRNAs in the Second Trimester From Pregnant Women Who Subsequently Developed Preeclampsia: Potential Candidates as Predictive Biomarkers and Pathway Analysis for Target Genes of miR-204-5p
por: Luizon, Marcelo R., et al.
Publicado: (2021)

Circulating miRNAs as Potential Marker for Pulmonary Hypertension
por: Wei, Chuanyu, et al.
Publicado: (2013)

Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene–Gene Interactions
por: Luizon, Marcelo R., et al.
Publicado: (2018)

Analysis of SIRT1 Expression in Plasma and in an In Vitro Model of Preeclampsia
por: Viana-Mattioli, Sarah, et al.
Publicado: (2020)

Assessment by ABPM verified the presence of hypertension in patients with self-reported hypertension, pregnant women, as well as differences between ethnicities in women aged 38-39 years in the Ribeirão Preto cohort
por: Brandão, Tetzi Oliveira, et al.
Publicado: (2022)

Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension
por: Amaral, Jefferson H., et al.
Publicado: (2015)

Pharmacogenomics And Hypertension: Current Insights
por: Oliveira-Paula, Gustavo H, et al.
Publicado: (2019)

Role Of MMP-2 and MMP-9 in Resistance to Drug Therapy in Patients with Resistant Hypertension
por: Lacerda, Leandro, et al.
Publicado: (2015)

Increased NOS coupling by the metabolite tetrahydrobiopterin (BH4) reduces preeclampsia/IUGR consequences
por: Chatre, Laurent, et al.
Publicado: (2022)

Markers of Endothelial Dysfunction Are Attenuated by Resveratrol in Preeclampsia
por: Bueno-Pereira, Thaina Omia, et al.
Publicado: (2022)

Maternal uterine artery Doppler in the first and second trimesters as screening method for hypertensive disorders and adverse perinatal outcomes in low-risk pregnancies
por: Scandiuzzi, Rosiane Maciel, et al.
Publicado: (2016)

Association of Adverse Pregnancy Outcomes With Hypertension 2 to 7 Years Postpartum
por: Haas, David M., et al.
Publicado: (2019)

The circulation in portal hypertension.
por: Witte, C. L., et al.
Publicado: (1975)

Circulating angiogenic factors are related to the severity of gestational hypertension and preeclampsia, and their adverse outcomes
por: Leaños-Miranda, Alfredo, et al.
Publicado: (2017)

Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study
por: Vermeulen Windsant, Iris C, et al.
Publicado: (2012)

Uterine vascular resistance and other maternal factors associated with the risk of developing hypertension during pregnancy
por: Martins, L.A.B., et al.
Publicado: (2020)

Prediction and prevention of preeclampsia by physicians in Brazil: An original study
por: da Cunha Filho, Edson Vieira, et al.
Publicado: (2022)

Symposium on Hæmodynamics in Pregnancy. IV. The Peripheral Circulation in Pregnancy
por: Burt, Catherine C.
Publicado: (1950)

Myeloperoxidase is not a good biomarker for preeclampsia prediction
por: Rocha-Penha, L., et al.
Publicado: (2017)

Author Correction: Myeloperoxidase is not a good biomarker for preeclampsia prediction
por: Rocha-Penha, L., et al.
Publicado: (2018)

Pregnancy-Induced Hypertension is Accompanied by Decreased Number of Circulating Endothelial Cells and Circulating Endothelial Progenitor Cells
por: Heimrath, Jerzy, et al.
Publicado: (2014)

Adrenergic receptor blockade attenuates placental ischemia‐induced hypertension
por: Spradley, Frank T., et al.
Publicado: (2018)

The Autonomic Regulation of Circulation and Adverse Events in Hypertensive Patients during Follow-Up Study
por: Mamontov, Oleg V., et al.
Publicado: (2019)

Intake of Energy Drinks Before and During Pregnancy and Adverse Pregnancy Outcomes
por: Ding, Ming, et al.
Publicado: (2023)

Sustained Elevated Circulating Activin A Impairs Global Longitudinal Strain in Pregnant Rats: A Potential Mechanism for Preeclampsia-Related Cardiac Dysfunction
por: Bakrania, Bhavisha A., et al.
Publicado: (2022)

Maternal hypertensive traits and adverse outcome in pregnancy: a Mendelian randomization study
por: Ardissino, Maddalena, et al.
Publicado: (2023)

The role of intervening pregnancy loss in the association between interpregnancy interval and adverse pregnancy outcomes
por: Tessema, Gizachew A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jsn6o7ekqk0q46go3f3q9a5i2u