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Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons

α-synuclein accumulation into dopaminergic neurons is a pathological hallmark of Parkinson’s disease. We previously demonstrated that fatty acid-binding protein 3 (FABP3) is critical for α-synuclein uptake and propagation to accumulate in dopaminergic neurons. FABP3 is abundant in dopaminergic neuro...

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Detalles Bibliográficos
Autores principales: Kawahata, Ichiro, Sekimori, Tomoki, Wang, Haoyang, Wang, Yanyan, Sasaoka, Toshikuni, Bousset, Luc, Melki, Ronald, Mizobata, Tomohiro, Kawata, Yasushi, Fukunaga, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826971/
https://www.ncbi.nlm.nih.gov/pubmed/33429895
http://dx.doi.org/10.3390/biomedicines9010049