Cargando…

Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii

A dozen Iris species (Iridaceae) are considered traditional remedies in Kurdistan, especially for treating inflammations. Phytochemical studies are still scarce. The information reported in the literature about Iris species growing in Kurdistan has been summarized in the first part of this paper, al...

Descripción completa

Detalles Bibliográficos
Autores principales: Amin, Hawraz Ibrahim M., Hussain, Faiq H. S., Najmaldin, Soran K., Thu, Zaw Min, Ibrahim, Mohammed Farhad, Gilardoni, Gianluca, Vidari, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827031/
https://www.ncbi.nlm.nih.gov/pubmed/33430398
http://dx.doi.org/10.3390/molecules26020264
_version_ 1783640663722557440
author Amin, Hawraz Ibrahim M.
Hussain, Faiq H. S.
Najmaldin, Soran K.
Thu, Zaw Min
Ibrahim, Mohammed Farhad
Gilardoni, Gianluca
Vidari, Giovanni
author_facet Amin, Hawraz Ibrahim M.
Hussain, Faiq H. S.
Najmaldin, Soran K.
Thu, Zaw Min
Ibrahim, Mohammed Farhad
Gilardoni, Gianluca
Vidari, Giovanni
author_sort Amin, Hawraz Ibrahim M.
collection PubMed
description A dozen Iris species (Iridaceae) are considered traditional remedies in Kurdistan, especially for treating inflammations. Phytochemical studies are still scarce. The information reported in the literature about Iris species growing in Kurdistan has been summarized in the first part of this paper, although, except for Iris persica, investigations have been performed on vegetal samples collected in countries different from Kurdistan. In the second part of the work, we have investigated, for the first time, the contents of the methanolic extracts of Iris postii aerial parts and rhizomes that were collected in Kurdistan. Both extracts exhibited a significant dose-dependent free radical scavenging and total antioxidant activities, comparable to those of ascorbic acid. Medium-pressure liquid chromatographic separations of the two extracts afforded l-tryptophan, androsin, isovitexin, swertisin, and 2″-O-α-l-rhamnopyranosyl swertisin from the aerial parts, whereas ε-viniferin, trans-resveratrol 3,4′-O-di-β-d-glucopyranoside, and isotectorigenin were isolated from the rhizomes. This is the first finding of the last three metabolites from an Iris species. The various remarkable biological activities of isolated compounds scientifically sustain the traditional use of I. postii as a medicinal plant.
format Online
Article
Text
id pubmed-7827031
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-78270312021-01-25 Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii Amin, Hawraz Ibrahim M. Hussain, Faiq H. S. Najmaldin, Soran K. Thu, Zaw Min Ibrahim, Mohammed Farhad Gilardoni, Gianluca Vidari, Giovanni Molecules Article A dozen Iris species (Iridaceae) are considered traditional remedies in Kurdistan, especially for treating inflammations. Phytochemical studies are still scarce. The information reported in the literature about Iris species growing in Kurdistan has been summarized in the first part of this paper, although, except for Iris persica, investigations have been performed on vegetal samples collected in countries different from Kurdistan. In the second part of the work, we have investigated, for the first time, the contents of the methanolic extracts of Iris postii aerial parts and rhizomes that were collected in Kurdistan. Both extracts exhibited a significant dose-dependent free radical scavenging and total antioxidant activities, comparable to those of ascorbic acid. Medium-pressure liquid chromatographic separations of the two extracts afforded l-tryptophan, androsin, isovitexin, swertisin, and 2″-O-α-l-rhamnopyranosyl swertisin from the aerial parts, whereas ε-viniferin, trans-resveratrol 3,4′-O-di-β-d-glucopyranoside, and isotectorigenin were isolated from the rhizomes. This is the first finding of the last three metabolites from an Iris species. The various remarkable biological activities of isolated compounds scientifically sustain the traditional use of I. postii as a medicinal plant. MDPI 2021-01-07 /pmc/articles/PMC7827031/ /pubmed/33430398 http://dx.doi.org/10.3390/molecules26020264 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Amin, Hawraz Ibrahim M.
Hussain, Faiq H. S.
Najmaldin, Soran K.
Thu, Zaw Min
Ibrahim, Mohammed Farhad
Gilardoni, Gianluca
Vidari, Giovanni
Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title_full Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title_fullStr Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title_full_unstemmed Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title_short Phytochemistry and Biological Activities of Iris Species Growing in Iraqi Kurdistan and Phenolic Constituents of the Traditional Plant Iris postii
title_sort phytochemistry and biological activities of iris species growing in iraqi kurdistan and phenolic constituents of the traditional plant iris postii
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827031/
https://www.ncbi.nlm.nih.gov/pubmed/33430398
http://dx.doi.org/10.3390/molecules26020264
work_keys_str_mv AT aminhawrazibrahimm phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT hussainfaiqhs phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT najmaldinsorank phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT thuzawmin phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT ibrahimmohammedfarhad phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT gilardonigianluca phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii
AT vidarigiovanni phytochemistryandbiologicalactivitiesofirisspeciesgrowinginiraqikurdistanandphenolicconstituentsofthetraditionalplantirispostii