A Safe GDNF and GDNF/BDNF Controlled Delivery System Improves Migration in Human Retinal Pigment Epithelial Cells and Survival in Retinal Ganglion Cells: Potential Usefulness in Degenerative Retinal Pathologies

We assessed the sustained delivery effect of poly (lactic-co-glycolic) acid (PLGA)/vitamin E (VitE) microspheres (MSs) loaded with glial cell-derived neurotrophic factor (GDNF) alone (GDNF-MSs) or combined with brain-derived neurotrophic factor (BDNF; GDNF/BDNF-MSs) on migration of the human adult r...

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Detalles Bibliográficos
Autores principales: Arranz-Romera, Alicia, Hernandez, Maria, Checa-Casalengua, Patricia, Garcia-Layana, Alfredo, Molina-Martinez, Irene T., Recalde, Sergio, Young, Michael J., Tucker, Budd A., Herrero-Vanrell, Rocío, Fernandez-Robredo, Patricia, Bravo-Osuna, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827036/
https://www.ncbi.nlm.nih.gov/pubmed/33440745
http://dx.doi.org/10.3390/ph14010050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827036/
https://www.ncbi.nlm.nih.gov/pubmed/33440745
http://dx.doi.org/10.3390/ph14010050

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