Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importance in Saudi Colorectal Cancer

Colorectal cancer (CRC) remains one of the main causes of death worldwide and in Saudi Arabia. The toxicity and the development of resistance against 5 fluorouracil 5FU pose increasing therapeutic difficulties, which necessitates the development of personalized drugs and drug combinations. Objective...

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Detalles Bibliográficos
Autores principales: Abdalla, Ashraf N., Malki, Waleed H., Qattan, Amal, Shahid, Imran, Hossain, Mohammad Akbar, Ahmed, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827067/
https://www.ncbi.nlm.nih.gov/pubmed/33440689
http://dx.doi.org/10.3390/molecules26020334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827067/
https://www.ncbi.nlm.nih.gov/pubmed/33440689
http://dx.doi.org/10.3390/molecules26020334

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