Cargando…

Assessment of Lifestyle Factors Helps to Identify Liver Fibrosis Due to Non-Alcoholic Fatty Liver Disease in Obesity

Only some individuals with obesity develop liver fibrosis due to non-alcoholic fatty liver disease (NAFLD-fibrosis). We determined whether detailed assessment of lifestyle factors in addition to physical, biochemical and genetic factors helps in identification of these patients. A total of 100 patie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lahelma, Mari, Luukkonen, Panu K., Qadri, Sami, Ahlholm, Noora, Lallukka-Brück, Susanna, Porthan, Kimmo, Juuti, Anne, Sammalkorpi, Henna, Penttilä, Anne K., Arola, Johanna, Orho-Melander, Marju, Yki-Järvinen, Hannele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827136/ https://www.ncbi.nlm.nih.gov/pubmed/33429859 http://dx.doi.org/10.3390/nu13010169

Ejemplares similares

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease
por: Luukkonen, Panu K., et al.
Publicado: (2022)

Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease
por: Qadri, Sami, et al.
Publicado: (2021)

Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) – an 11-Year Prospective Study
por: Lallukka, Susanna, et al.
Publicado: (2017)

Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis
por: Luukkonen, Panu K., et al.
Publicado: (2023)

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
por: Luukkonen, Panu K., et al.
Publicado: (2018)

Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease
por: Tamaki, Nobuharu, et al.
Publicado: (2022)

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
por: Jian, Ching, et al.
Publicado: (2020)

The quest for the missing links in fatty liver genetics: Deep learning to the rescue!
por: Qadri, Sami, et al.
Publicado: (2022)

Overfeeding Saturated Fat Increases LDL (Low-Density Lipoprotein) Aggregation Susceptibility While Overfeeding Unsaturated Fat Decreases Proteoglycan-Binding of Lipoproteins
por: Ruuth, Maija, et al.
Publicado: (2021)

Continuous Grading of Early Fibrosis in NAFLD Using Label-Free Imaging: A Proof-of-Concept Study
por: Pirhonen, Juho, et al.
Publicado: (2016)

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance
por: Yki-Järvinen, Hannele
Publicado: (2015)

Bile Reflux is a Common Finding in the Gastric Pouch After One Anastomosis Gastric Bypass
por: Saarinen, Tuure, et al.
Publicado: (2019)

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
por: Luukkonen, Panu K., et al.
Publicado: (2020)

Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD—A Systematic Review
por: Petäjä, Elina M., et al.
Publicado: (2016)

In vitro Effects of Bacterial Exposure on Secretion of Zonulin Family Peptides and Their Detection in Human Tissue Samples
por: Jian, Ching, et al.
Publicado: (2022)

Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
por: Orešič, Matej, et al.
Publicado: (2013)

Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver
por: Kotronen, Anna, et al.
Publicado: (2009)

A new adult appendicitis score improves diagnostic accuracy of acute appendicitis - a prospective study
por: Sammalkorpi, Henna E, et al.
Publicado: (2014)

OSBP-Related Proteins (ORPs) in Human Adipose Depots and Cultured Adipocytes: Evidence for Impacts on the Adipocyte Phenotype
por: Zhou, You, et al.
Publicado: (2012)

New Insights into Impaired Muscle Glycogen Synthesis: More a Problem of Muscle Contractility Than of Glucose Tolerance
por: Groop, Leif, et al.
Publicado: (2008)

The gut microbiome as a target for prevention and treatment of hyperglycaemia in type 2 diabetes: from current human evidence to future possibilities
por: Brunkwall, Louise, et al.
Publicado: (2017)

Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD
por: Petäjä, Elina M., et al.
Publicado: (2016)

Performance of imaging studies in patients with suspected appendicitis after stratification with adult appendicitis score
por: Sammalkorpi, Henna E., et al.
Publicado: (2017)

Is There Evidence to Support Use of Premixed or Prandial Insulin Regimens in Insulin-Naive or Previously Insulin-Treated Type 2 Diabetic Patients?
por: Yki-Järvinen, Hannele, et al.
Publicado: (2013)

A favorable lifestyle lowers the risk of coronary artery disease consistently across strata of non-modifiable risk factors in a population-based cohort
por: Dimovski, Kristian, et al.
Publicado: (2019)

Higher Levels of Serum Zonulin May Rather Be Associated with Increased Risk of Obesity and Hyperlipidemia, Than with Gastrointestinal Symptoms or Disease Manifestations
por: Ohlsson, Bodil, et al.
Publicado: (2017)

Polygenic Risk Score for Coronary Heart Disease Modifies the Elevated Risk by Cigarette Smoking for Disease Incidence
por: Hindy, George, et al.
Publicado: (2018)

Selenoprotein-P Deficiency Predicts Cardiovascular Disease and Death
por: Schomburg, Lutz, et al.
Publicado: (2019)

Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals
por: Rosqvist, Fredrik, et al.
Publicado: (2020)

A genetic risk score for fasting plasma glucose is independently associated with arterial stiffness: a Mendelian randomization study
por: Gottsäter, Mikael, et al.
Publicado: (2018)

A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8
por: Drake, Isabel, et al.
Publicado: (2017)

Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank
por: Fall, Tove, et al.
Publicado: (2018)

‘No research without perfect methods’: a problematic approach in epidemiology
por: Wuopio, Jonas, et al.
Publicado: (2023)

Influence of Ethnicity on the Accuracy of Non-Invasive Scores Predicting Non-Alcoholic Fatty Liver Disease
por: Xia, Ming-Feng, et al.
Publicado: (2016)

The associations between red cell distribution width and plasma proteins in a general population
por: Pan, Jingxue, et al.
Publicado: (2021)

Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men
por: Teleka, Stanley, et al.
Publicado: (2022)

The insertion/deletion variation in the α(2B)-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes
por: Snapir, Amir, et al.
Publicado: (2003)

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease
por: Hyötyläinen, Tuulia, et al.
Publicado: (2016)

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
por: Beer, Nicola L., et al.
Publicado: (2009)

Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes
por: Huvinen, Emilia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a9sivofh9ec9ej0a2sjsj58ana