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Aflatoxin Detoxification Using Microorganisms and Enzymes

Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the produc...

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Autores principales: Guan, Yun, Chen, Jia, Nepovimova, Eugenie, Long, Miao, Wu, Wenda, Kuca, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827145/
https://www.ncbi.nlm.nih.gov/pubmed/33435382
http://dx.doi.org/10.3390/toxins13010046
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author Guan, Yun
Chen, Jia
Nepovimova, Eugenie
Long, Miao
Wu, Wenda
Kuca, Kamil
author_facet Guan, Yun
Chen, Jia
Nepovimova, Eugenie
Long, Miao
Wu, Wenda
Kuca, Kamil
author_sort Guan, Yun
collection PubMed
description Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs.
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spelling pubmed-78271452021-01-25 Aflatoxin Detoxification Using Microorganisms and Enzymes Guan, Yun Chen, Jia Nepovimova, Eugenie Long, Miao Wu, Wenda Kuca, Kamil Toxins (Basel) Review Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs. MDPI 2021-01-09 /pmc/articles/PMC7827145/ /pubmed/33435382 http://dx.doi.org/10.3390/toxins13010046 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Guan, Yun
Chen, Jia
Nepovimova, Eugenie
Long, Miao
Wu, Wenda
Kuca, Kamil
Aflatoxin Detoxification Using Microorganisms and Enzymes
title Aflatoxin Detoxification Using Microorganisms and Enzymes
title_full Aflatoxin Detoxification Using Microorganisms and Enzymes
title_fullStr Aflatoxin Detoxification Using Microorganisms and Enzymes
title_full_unstemmed Aflatoxin Detoxification Using Microorganisms and Enzymes
title_short Aflatoxin Detoxification Using Microorganisms and Enzymes
title_sort aflatoxin detoxification using microorganisms and enzymes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827145/
https://www.ncbi.nlm.nih.gov/pubmed/33435382
http://dx.doi.org/10.3390/toxins13010046
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