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Aflatoxin Detoxification Using Microorganisms and Enzymes
Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the produc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827145/ https://www.ncbi.nlm.nih.gov/pubmed/33435382 http://dx.doi.org/10.3390/toxins13010046 |
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author | Guan, Yun Chen, Jia Nepovimova, Eugenie Long, Miao Wu, Wenda Kuca, Kamil |
author_facet | Guan, Yun Chen, Jia Nepovimova, Eugenie Long, Miao Wu, Wenda Kuca, Kamil |
author_sort | Guan, Yun |
collection | PubMed |
description | Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs. |
format | Online Article Text |
id | pubmed-7827145 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78271452021-01-25 Aflatoxin Detoxification Using Microorganisms and Enzymes Guan, Yun Chen, Jia Nepovimova, Eugenie Long, Miao Wu, Wenda Kuca, Kamil Toxins (Basel) Review Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs. MDPI 2021-01-09 /pmc/articles/PMC7827145/ /pubmed/33435382 http://dx.doi.org/10.3390/toxins13010046 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Guan, Yun Chen, Jia Nepovimova, Eugenie Long, Miao Wu, Wenda Kuca, Kamil Aflatoxin Detoxification Using Microorganisms and Enzymes |
title | Aflatoxin Detoxification Using Microorganisms and Enzymes |
title_full | Aflatoxin Detoxification Using Microorganisms and Enzymes |
title_fullStr | Aflatoxin Detoxification Using Microorganisms and Enzymes |
title_full_unstemmed | Aflatoxin Detoxification Using Microorganisms and Enzymes |
title_short | Aflatoxin Detoxification Using Microorganisms and Enzymes |
title_sort | aflatoxin detoxification using microorganisms and enzymes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827145/ https://www.ncbi.nlm.nih.gov/pubmed/33435382 http://dx.doi.org/10.3390/toxins13010046 |
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