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Mono(ADP-ribosyl)ation Enzymes and NAD(+) Metabolism: A Focus on Diseases and Therapeutic Perspectives
Mono(ADP-ribose) transferases and mono(ADP-ribosyl)ating sirtuins use NAD(+) to perform the mono(ADP-ribosyl)ation, a simple form of post-translational modification of proteins and, in some cases, of nucleic acids. The availability of NAD(+) is a limiting step and an essential requisite for NAD(+) c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827148/ https://www.ncbi.nlm.nih.gov/pubmed/33440786 http://dx.doi.org/10.3390/cells10010128 |