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Mono(ADP-ribosyl)ation Enzymes and NAD(+) Metabolism: A Focus on Diseases and Therapeutic Perspectives

Mono(ADP-ribose) transferases and mono(ADP-ribosyl)ating sirtuins use NAD(+) to perform the mono(ADP-ribosyl)ation, a simple form of post-translational modification of proteins and, in some cases, of nucleic acids. The availability of NAD(+) is a limiting step and an essential requisite for NAD(+) c...

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Detalles Bibliográficos
Autores principales:	Poltronieri, Palmiro, Celetti, Angela, Palazzo, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827148/ https://www.ncbi.nlm.nih.gov/pubmed/33440786 http://dx.doi.org/10.3390/cells10010128

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