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Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre
The Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress and autophagic dysfunction. Mitochondria are the...
Autores principales: | Castejón-Vega, Beatriz, Battino, Maurizio, Quiles, José L., Bullon, Beatriz, Cordero, Mario D., Bullón, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827181/ https://www.ncbi.nlm.nih.gov/pubmed/33445524 http://dx.doi.org/10.3390/antiox10010095 |
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