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Overexpression of the Bacteriophage T4 motB Gene Alters H-NS Dependent Repression of Specific Host DNA

The bacteriophage T4 early gene product MotB binds tightly but nonspecifically to DNA, copurifies with the host Nucleoid Associated Protein (NAP) H-NS in the presence of DNA and improves T4 fitness. However, the T4 transcriptome is not significantly affected by a motB knockdown. Here we have investi...

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Detalles Bibliográficos
Autores principales: Patterson-West, Jennifer, Tai, Chin-Hsien, Son, Bokyung, Hsieh, Meng-Lun, Iben, James R., Hinton, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827196/
https://www.ncbi.nlm.nih.gov/pubmed/33435393
http://dx.doi.org/10.3390/v13010084