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HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia

SIMPLE SUMMARY: Hypoxia is one of the characteristics of most solid tumors and induces cell resistant to chemotherapy. In this paper, we established a hypoxia model in both in vitro and in vivo to investigate the mechanisms of Sorafenib resistance in Hepatocellular carcinoma (HCC). Here, we observed...

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Detalles Bibliográficos
Autores principales:	Liao, Yan, Yang, Yue, Pan, Di, Ding, Youxiang, Zhang, Heng, Ye, Yuting, Li, Jia, Zhao, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827218/ https://www.ncbi.nlm.nih.gov/pubmed/33440739 http://dx.doi.org/10.3390/cancers13020243

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