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Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon

The present study aims to investigate the properties of biopolymers extracted from a Lebanese onion non edible plant. The extraction was performed under mild conditions by varying the percentage of ultra-sound (US) treatment duration to a total extraction time of 30 min (0, 50, 100% US). The extract...

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Autores principales: Medlej, Mohammad Kazem, Batoul, Cherri, Olleik, Hamza, Li, Suming, Hijazi, Akram, Nasser, Ghassan, Maresca, Marc, Pochat-Bohatier, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827233/
https://www.ncbi.nlm.nih.gov/pubmed/33430440
http://dx.doi.org/10.3390/antiox10010068
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author Medlej, Mohammad Kazem
Batoul, Cherri
Olleik, Hamza
Li, Suming
Hijazi, Akram
Nasser, Ghassan
Maresca, Marc
Pochat-Bohatier, Céline
author_facet Medlej, Mohammad Kazem
Batoul, Cherri
Olleik, Hamza
Li, Suming
Hijazi, Akram
Nasser, Ghassan
Maresca, Marc
Pochat-Bohatier, Céline
author_sort Medlej, Mohammad Kazem
collection PubMed
description The present study aims to investigate the properties of biopolymers extracted from a Lebanese onion non edible plant. The extraction was performed under mild conditions by varying the percentage of ultra-sound (US) treatment duration to a total extraction time of 30 min (0, 50, 100% US). The extracts were characterized using FTIR, SEC, GC-MS, TGA, and DSC analyses. The composition of the extracts was determined from the total carbohydrate content and protein content measurements. The thermal analyses indicate that all samples have high thermal stability. The antioxidant activities of the extracts were investigated, using β-carotene bleaching, scavenging activity of ABTS, metal chelating ability, and total antioxidant activity tests. The results indicate that the 50% US treatment leads to the best antioxidant activity. Biocompatibility of the extracts was evaluated using hemolysis and cytotoxicity assays. The results showed that 0 and 50% US samples are not toxic to human cells, in contrary to 100% US.
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spelling pubmed-78272332021-01-25 Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon Medlej, Mohammad Kazem Batoul, Cherri Olleik, Hamza Li, Suming Hijazi, Akram Nasser, Ghassan Maresca, Marc Pochat-Bohatier, Céline Antioxidants (Basel) Article The present study aims to investigate the properties of biopolymers extracted from a Lebanese onion non edible plant. The extraction was performed under mild conditions by varying the percentage of ultra-sound (US) treatment duration to a total extraction time of 30 min (0, 50, 100% US). The extracts were characterized using FTIR, SEC, GC-MS, TGA, and DSC analyses. The composition of the extracts was determined from the total carbohydrate content and protein content measurements. The thermal analyses indicate that all samples have high thermal stability. The antioxidant activities of the extracts were investigated, using β-carotene bleaching, scavenging activity of ABTS, metal chelating ability, and total antioxidant activity tests. The results indicate that the 50% US treatment leads to the best antioxidant activity. Biocompatibility of the extracts was evaluated using hemolysis and cytotoxicity assays. The results showed that 0 and 50% US samples are not toxic to human cells, in contrary to 100% US. MDPI 2021-01-07 /pmc/articles/PMC7827233/ /pubmed/33430440 http://dx.doi.org/10.3390/antiox10010068 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Medlej, Mohammad Kazem
Batoul, Cherri
Olleik, Hamza
Li, Suming
Hijazi, Akram
Nasser, Ghassan
Maresca, Marc
Pochat-Bohatier, Céline
Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title_full Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title_fullStr Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title_full_unstemmed Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title_short Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon
title_sort antioxidant activity and biocompatibility of fructo-polysaccharides extracted from a wild species of ornithogalum from lebanon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827233/
https://www.ncbi.nlm.nih.gov/pubmed/33430440
http://dx.doi.org/10.3390/antiox10010068
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