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Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties

The genus Parkia (Fabaceae, Subfamily, Mimosoideae) comprises about 34 species of mostly evergreen trees widely distributed across neotropics, Asia, and Africa. This review aims to provide an overview of the current status of the species from the genus Parkia in terms of its relationship between its...

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Autores principales: Saleh, Mohammed S. M., Jalil, Juriyati, Zainalabidin, Satirah, Asmadi, Ahmad Yusof, Mustafa, Nor Hidayah, Kamisah, Yusof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827335/
https://www.ncbi.nlm.nih.gov/pubmed/33435507
http://dx.doi.org/10.3390/ijms22020618
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author Saleh, Mohammed S. M.
Jalil, Juriyati
Zainalabidin, Satirah
Asmadi, Ahmad Yusof
Mustafa, Nor Hidayah
Kamisah, Yusof
author_facet Saleh, Mohammed S. M.
Jalil, Juriyati
Zainalabidin, Satirah
Asmadi, Ahmad Yusof
Mustafa, Nor Hidayah
Kamisah, Yusof
author_sort Saleh, Mohammed S. M.
collection PubMed
description The genus Parkia (Fabaceae, Subfamily, Mimosoideae) comprises about 34 species of mostly evergreen trees widely distributed across neotropics, Asia, and Africa. This review aims to provide an overview of the current status of the species from the genus Parkia in terms of its relationship between its phytochemistry and medical uses. Comprehensive information on Parkia species was retrieved from electronic databases, which were Web of Science, ScienceDirect, PubMed, and Google Scholar. This review identified nine species from genus Parkia with properties of medicinal use. They are used traditionally to treat several ailments, such as diabetes, diarrhea, wounds, hypertension, cough, chronic piles, conjunctivitis, and measles. The most common species studied are P. biglobosa, P. speciosa, P. javanica, P. bicolor, P. biglandulosa, P. filicoidea, and P. clappertoniana. A considerable number of secondary metabolites, such as terpenoids, phenolic acids, flavonoids (aglycone and glycosides), and numerous volatile compounds have been identified in this genus, which are responsible for their diverse pharmacological activities. Their extracts, pure compounds and seed lectins have been reported for their anticancer, antimicrobial, antihypertensive, antiulcer, antidiabetic, anti-inflammatory, antioxidant, antimalarial, hepatoprotective, and antidiarrheal activities. The information gathered in this review might be of help for future studies in terms of the current knowledge on the link between the phytochemical components and medicinal uses. This could facilitate more discoveries on its potentials particularly in the pharmacological characteristics and potential to be developed into modern medicines.
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spelling pubmed-78273352021-01-25 Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties Saleh, Mohammed S. M. Jalil, Juriyati Zainalabidin, Satirah Asmadi, Ahmad Yusof Mustafa, Nor Hidayah Kamisah, Yusof Int J Mol Sci Review The genus Parkia (Fabaceae, Subfamily, Mimosoideae) comprises about 34 species of mostly evergreen trees widely distributed across neotropics, Asia, and Africa. This review aims to provide an overview of the current status of the species from the genus Parkia in terms of its relationship between its phytochemistry and medical uses. Comprehensive information on Parkia species was retrieved from electronic databases, which were Web of Science, ScienceDirect, PubMed, and Google Scholar. This review identified nine species from genus Parkia with properties of medicinal use. They are used traditionally to treat several ailments, such as diabetes, diarrhea, wounds, hypertension, cough, chronic piles, conjunctivitis, and measles. The most common species studied are P. biglobosa, P. speciosa, P. javanica, P. bicolor, P. biglandulosa, P. filicoidea, and P. clappertoniana. A considerable number of secondary metabolites, such as terpenoids, phenolic acids, flavonoids (aglycone and glycosides), and numerous volatile compounds have been identified in this genus, which are responsible for their diverse pharmacological activities. Their extracts, pure compounds and seed lectins have been reported for their anticancer, antimicrobial, antihypertensive, antiulcer, antidiabetic, anti-inflammatory, antioxidant, antimalarial, hepatoprotective, and antidiarrheal activities. The information gathered in this review might be of help for future studies in terms of the current knowledge on the link between the phytochemical components and medicinal uses. This could facilitate more discoveries on its potentials particularly in the pharmacological characteristics and potential to be developed into modern medicines. MDPI 2021-01-09 /pmc/articles/PMC7827335/ /pubmed/33435507 http://dx.doi.org/10.3390/ijms22020618 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Saleh, Mohammed S. M.
Jalil, Juriyati
Zainalabidin, Satirah
Asmadi, Ahmad Yusof
Mustafa, Nor Hidayah
Kamisah, Yusof
Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title_full Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title_fullStr Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title_full_unstemmed Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title_short Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties
title_sort genus parkia: phytochemical, medicinal uses, and pharmacological properties
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827335/
https://www.ncbi.nlm.nih.gov/pubmed/33435507
http://dx.doi.org/10.3390/ijms22020618
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