Cargando…

Activation of Glutamate Transporter-1 (GLT-1) Confers Sex-Dependent Neuroprotection in Brain Ischemia

Stroke is one of the leading causes of long-term disability. During ischemic stroke, glutamate is released, reuptake processes are impaired, and glutamate promotes excitotoxic neuronal death. Astrocytic glutamate transporter 1 (GLT-1) is the major transporter responsible for removing excess glutamat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tejeda-Bayron, Flavia A., Rivera-Aponte, David E., Malpica-Nieves, Christian J., Maldonado-Martínez, Gerónimo, Maldonado, Héctor M., Skatchkov, Serguei N., Eaton, Misty J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827447/ https://www.ncbi.nlm.nih.gov/pubmed/33429955 http://dx.doi.org/10.3390/brainsci11010076

Ejemplares similares

Erratum: Tejeda-Bayron et al. Activation of Glutamate Transporter-1 (GLT-1) Confers Sex-Dependent Neuroprotection in Brain Ischemia. Brain Sci. 2021, 11, 76
por: Tejeda-Bayron, Flavia A., et al.
Publicado: (2021)

Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice
por: Méndez-González, Miguel P., et al.
Publicado: (2020)

Impairment of Neuronal Glutamate Uptake and Modulation of the Glutamate Transporter GLT-1 Induced by Retinal Ischemia
por: Russo, Rossella, et al.
Publicado: (2013)

Uptake of Biotinylated Spermine in Astrocytes: Effect of Cx43 siRNA, HIV-Tat Protein and Polyamine Transport Inhibitor on Polyamine Uptake
por: Malpica-Nieves, Christian J., et al.
Publicado: (2021)

The Effect of GLT-1 Upregulation on Extracellular Glutamate Dynamics
por: Wilkie, Crystal M., et al.
Publicado: (2021)

PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice
por: Wang, Yuqing, et al.
Publicado: (2022)

Changes in the Localization of Polyamine Spermidine in the Rat Retina with Age
por: Ríos, David S., et al.
Publicado: (2023)

Glutamate Transporters GltS, GltP and GltI Are Involved in Escherichia coli Tolerance In Vitro and Pathogenicity in Mouse Urinary Tract Infections
por: Niu, Hongxia, et al.
Publicado: (2023)

Glutamate Transporter GLT1 Expression in Alzheimer Disease and Dementia With Lewy Bodies
por: Garcia-Esparcia, Paula, et al.
Publicado: (2018)

Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus
por: Rimmele, Theresa S., et al.
Publicado: (2021)

The Polyamine Spermine Potentiates the Propagation of Negatively Charged Molecules through the Astrocytic Syncytium
por: Benedikt, Jan, et al.
Publicado: (2022)

Characterization of the Visceral Antinociceptive Effect of Glial Glutamate Transporter GLT-1 Upregulation by Ceftriaxone
por: Roman, K., et al.
Publicado: (2012)

The role of hippocampal glial glutamate transporter (GLT‐1) in morphine‐induced behavioral responses
por: Saeedi, Negin, et al.
Publicado: (2021)

Transport mechanism of a glutamate transporter homologue Glt(Ph)
por: Ji, Yurui, et al.
Publicado: (2016)

Astrocytic Glutamate Transporter 1 (GLT1) Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice
por: Jia, Yun-Fang, et al.
Publicado: (2020)

Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats
por: Ge, Yuhang, et al.
Publicado: (2022)

Binding and transport of D-aspartate by the glutamate transporter homolog Glt(Tk)
por: Arkhipova, Valentina, et al.
Publicado: (2019)

The high‐energy transition state of the glutamate transporter homologue GltPh
por: Huysmans, Gerard H M, et al.
Publicado: (2020)

Position of the Third Na(+) Site in the Aspartate Transporter Glt(Ph) and the Human Glutamate Transporter, EAAT1
por: Bastug, Turgut, et al.
Publicado: (2012)

Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone
por: R Zimmer, Eduardo, et al.
Publicado: (2015)

GLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate
por: Kabakov, Anatoli Y., et al.
Publicado: (2015)

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii
por: David, Clément N., et al.
Publicado: (2016)

TM4 of the glutamate transporter GLT-1 experiences substrate-induced motion during the transport cycle
por: Rong, Xiuliang, et al.
Publicado: (2016)

The Expression of GLAST and GLT1 in a Transient Cerebral Ischemia Mongolian Gerbil Model
por: Shen, Yanling, et al.
Publicado: (2020)

Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice
por: Ding, Xiu-Fang, et al.
Publicado: (2017)

The archaeal glutamate transporter homologue Glt(Ph) shows heterogeneous substrate binding
por: Reddy, Krishna D., et al.
Publicado: (2022)

Up-Regulation of TREK-2 Potassium Channels in Cultured Astrocytes Requires De Novo Protein Synthesis: Relevance to Localization of TREK-2 Channels in Astrocytes after Transient Cerebral Ischemia
por: Rivera-Pagán, Aixa F., et al.
Publicado: (2015)

PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer’s disease
por: Perrin, Florian, et al.
Publicado: (2023)

Riluzole neuroprotection in a parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation
por: Carbone, Marica, et al.
Publicado: (2012)

Upregulation of GLT-1 via PI3K/Akt Pathway Contributes to Neuroprotection Induced by Dexmedetomidine
por: Peng, Mengyuan, et al.
Publicado: (2019)

Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures
por: Kovács, Zsolt, et al.
Publicado: (2022)

Proximity of Transmembrane Segments 5 and 8 of the Glutamate Transporter GLT-1 Inferred from Paired Cysteine Mutagenesis
por: Zhang, Xiuping, et al.
Publicado: (2011)

Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy
por: Sicot, Géraldine, et al.
Publicado: (2017)

Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke
por: Harvey, Brandon K., et al.
Publicado: (2011)

Retraction Note: Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice
por: Ding, Xiu-Fang, et al.
Publicado: (2023)

Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways
por: Zhang, Xiao, et al.
Publicado: (2013)

Pre-Ischemic Treadmill Training for Prevention of Ischemic Brain Injury via Regulation of Glutamate and Its Transporter GLT-1
por: Yang, Xiaojiao, et al.
Publicado: (2012)

Effects of MS-153 on chronic ethanol consumption and GLT1 modulation of glutamate levels in male alcohol-preferring rats
por: Alhaddad, Hasan, et al.
Publicado: (2014)

Neuronal activity mediated regulation of glutamate transporter GLT‐1 surface diffusion in rat astrocytes in dissociated and slice cultures
por: Al Awabdh, Sana, et al.
Publicado: (2016)

Yokukansan, a Traditional Japanese Medicine, Enhances the Glutamate Transporter GLT-1 Function in Cultured Rat Cortical Astrocytes
por: Ueki, Toshiyuki, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cenn1vcq5dl9rv7qi4mh4tqujl