Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues

In this study, an initial in vivo evaluation of a new amikacin-deoxycholate hydrophobic salt aimed at potentiating amikacin action against hard-to-treat lung infections was undertaken by quantifying, for the first time, amikacin in whole blood. Pharmacokinetic evaluation after intranasal administrat...

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Detalles Bibliográficos
Autores principales: Xiroudaki, Styliani, Ianni, Federica, Sabbatini, Samuele, Roselletti, Elena, Monari, Claudia, Sardella, Roccaldo, Vecchiarelli, Anna, Giovagnoli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827485/
https://www.ncbi.nlm.nih.gov/pubmed/33435166
http://dx.doi.org/10.3390/pharmaceutics13010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827485/
https://www.ncbi.nlm.nih.gov/pubmed/33435166
http://dx.doi.org/10.3390/pharmaceutics13010085

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