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SIRT1 Activation Attenuates the Cardiac Dysfunction Induced by Endothelial Cell-Specific Deletion of CRIF1

The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy. We developed an endothelial cell-specific CRIF1 deletion mouse to ascert...

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Detalles Bibliográficos
Autores principales:	Piao, Shuyu, Lee, Ikjun, Jin, Seon-Ah, Kim, Seonhee, Nagar, Harsha, Choi, Su-jeong, Jeon, Byeong Hwa, Kim, Cuk-Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827654/ https://www.ncbi.nlm.nih.gov/pubmed/33430144 http://dx.doi.org/10.3390/biomedicines9010052

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