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Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHFR is also required in the maintenance of heterochr...
Autores principales: | Lim, Kim Kiat, Teo, Hwei Yee, Tan, Yuan Yee, Zeng, Yi Bing, Lam, Ulysses Tsz Fung, Choolani, Mahesh, Chen, Ee Sin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827777/ https://www.ncbi.nlm.nih.gov/pubmed/33440639 http://dx.doi.org/10.3390/ijms22020639 |
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