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Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHFR is also required in the maintenance of heterochr...

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Detalles Bibliográficos
Autores principales: Lim, Kim Kiat, Teo, Hwei Yee, Tan, Yuan Yee, Zeng, Yi Bing, Lam, Ulysses Tsz Fung, Choolani, Mahesh, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827777/
https://www.ncbi.nlm.nih.gov/pubmed/33440639
http://dx.doi.org/10.3390/ijms22020639

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