The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain

Vinculin and its heart-specific splice variant metavinculin are key regulators of cell adhesion processes. These membrane-bound cytoskeletal proteins regulate the cell shape by binding to several other proteins at cell–cell and cell–matrix junctions. Vinculin and metavinculin link integrin adhesion...

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Detalles Bibliográficos
Autores principales: Rangarajan, Erumbi S., Izard, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827843/
https://www.ncbi.nlm.nih.gov/pubmed/33440717
http://dx.doi.org/10.3390/ijms22020645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827843/
https://www.ncbi.nlm.nih.gov/pubmed/33440717
http://dx.doi.org/10.3390/ijms22020645

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