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Radiation-Activated PI3K/AKT Pathway Promotes the Induction of Cancer Stem-Like Cells via the Upregulation of SOX2 in Colorectal Cancer

The current treatment strategy for patients with aggressive colorectal cancer has been hampered by resistance to radiotherapy and chemotherapy due to the existence of cancer stem-like cells (CSCs). Recent studies have shown that SOX2 expression plays an important role in the maintenance of CSC prope...

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Detalles Bibliográficos
Autores principales: Park, Ji-Hye, Kim, Young-Heon, Shim, Sehwan, Kim, Areumnuri, Jang, Hyosun, Lee, Su-Jae, Park, Sunhoo, Seo, Songwon, Jang, Won Il, Lee, Seung Bum, Kim, Min-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827893/
https://www.ncbi.nlm.nih.gov/pubmed/33445526
http://dx.doi.org/10.3390/cells10010135