Splenectomy Prior to Experimental Induction of Autoimmune Hepatitis Promotes More Severe Hepatic Inflammation, Production of IL-17 and Apoptosis

Autoimmune hepatitis (AIH) is detected at a late stage in the course of the disease. Therefore, induction and etiology are largely unclear. It is controversial if the induction of autoimmunity occurs in the liver or in the spleen. In our experimental murine AIH model, the induction of autoimmunity d...

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Detalles Bibliográficos
Autores principales: Buitrago-Molina, Laura Elisa, Dywicki, Janine, Noyan, Fatih, Trippler, Martin, Pietrek, Julia, Schlue, Jerome, Manns, Michael P., Wedemeyer, Heiner, Jaeckel, Elmar, Hardtke-Wolenski, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827897/
https://www.ncbi.nlm.nih.gov/pubmed/33435354
http://dx.doi.org/10.3390/biomedicines9010058

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