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Structure-Activity Relationship of Mono-Ion Complexes for Plasmid DNA Delivery by Muscular Injection

The structure-activity relationship of mono-ion complexes (MICs) for plasmid DNA (pDNA) delivery by muscular injection is demonstrated. MICs were formed between pDNA and monocationic poly(ethylene glycol) (PEG) macromolecules. As monocationic PEGs, the ω-amide-pentylimidazolium (APe-Im) end-modified...

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Detalles Bibliográficos
Autores principales:	Mori, Amika, Kobayashi, Yuki, Nirasawa, Kei, Negishi, Yoichi, Asayama, Shoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828051/ https://www.ncbi.nlm.nih.gov/pubmed/33430003 http://dx.doi.org/10.3390/pharmaceutics13010078

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